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Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx218
Abstract: Abstract One third of tumor suppressors are haploinsufficient transcriptional regulators, yet it remains unknown how a 50% reduction of a transcription factor is translated at the cis-regulatory level into a malignant transcriptional program. We studied…
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Keywords:
haploinsufficient tumor;
cux1;
distal enhancers;
target ... See more keywords