Chokepoints in Mechanical Coupling Associated with Allosteric Proteins: The Pyruvate Kinase Example.
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DOI: 10.1016/j.bpj.2019.03.026
Abstract: Although the critical role of allostery in controlling enzymatic processes is well appreciated, there is a current dearth in our understanding of its underlying mechanisms, including communication between binding sites. One potential key aspect of… read more here.
Keywords: distant parts; pyruvate kinase; parts protein; coupling ... See more keywords