Immunohistochemical characterization of bipolar cells in four distantly related avian species
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25443
Abstract: Visual (and probably also magnetic) signal processing starts at the first synapse, at which photoreceptors contact different types of bipolar cells, thereby feeding information into different processing channels. In the chicken retina, 15 and 22… read more here.
Keywords: cell types; distantly related; bipolar cell; bipolar cells ... See more keywords
The piggyBac-derived protein 5 (PGBD5) transposes both the closely and the distantly related piggyBac-like elements Tcr-pble and Ifp2.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.166839
Abstract: The vertebrate piggyBac derived transposase 5 (PGBD5) encodes a domesticated transposase, which is active and able to transpose its distantly related piggyBac-like element (pble), Ifp2. This raised the question whether PGBD5 would be more effective… read more here.
Keywords: tcr pble; pble ifp2; pgbd5; piggybac derived ... See more keywords
Furcation and fusion: The phylogenetics of evolutionary novelty.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.09.015
Abstract: Novelty and innovation are fundamental yet relatively understudied concepts in evolution. We may study the history and provenance of novelty using phylogenetics, where key questions include when evolution occurs by tree-like branching and when it… read more here.
Keywords: evolution; furcation; related parts; fusion ... See more keywords
A novel strategy for designing the magic shotguns for distantly related target pairs
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac621
Abstract: Due to its promising capacity in improving drug efficacy, polypharmacology has emerged to be a new theme in the drug discovery of complex disease. In the process of novel multi-target drugs (MTDs) discovery, in silico… read more here.
Keywords: target pairs; related target; distantly related; novel strategy ... See more keywords
#31: Children with Invasive S. aureus Infection Produce Broadly Neutralizing Antibodies Against Distantly Related Variants of the Cytotoxin LukAB
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piab031.024
Abstract: Staphylococcus aureus is the most common invasive bacterial pathogen in children, and novel targets of intervention are urgently needed. The two-component leukotoxin, LukAB, is critical for S. aureus targeting and killing of human neutrophils and… read more here.
Keywords: invasive aureus; lukab; related variants; infection ... See more keywords
A multi-tasking stomach: functional coexistence of acid–peptic digestion and defensive body inflation in three distantly related vertebrate lineages
Sign Up to like & getrecommendations! Published in 2022 at "Biology Letters"
DOI: 10.1098/rsbl.2021.0583
Abstract: Puffer and porcupine fishes (families Diodontidae and Tetraodontidae, order Tetradontiformes) are known for their extraordinary ability to triple their body size by swallowing and retaining large amounts of seawater in their accommodating stomachs. This inflation… read more here.
Keywords: body; stomach; loss; acid peptic ... See more keywords
Comparing dormancy in two distantly related tunicates reveals morphological, molecular, and ecological convergences and repeated co-option
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1101/2022.02.09.477513
Abstract: Many asexually-propagating marine invertebrates can survive extreme environmental conditions by developing dormant structures, i.e., morphologically simplified bodies that retain the capacity to completely regenerate a functional adult when conditions return to normal. Here, we examine… read more here.
Keywords: two distantly; dormancy; distantly related; dormant structures ... See more keywords
Discovery and Biosynthesis of the Antibiotic Bicyclomycin in Distantly Related Bacterial Classes
Sign Up to like & getrecommendations! Published in 2018 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02828-17
Abstract: ABSTRACT Bicyclomycin (BCM) is a clinically promising antibiotic that is biosynthesized by Streptomyces cinnamoneus DSM 41675. BCM is structurally characterized by a core cyclo(l-Ile-l-Leu) 2,5-diketopiperazine (DKP) that is extensively oxidized. Here, we identify the BCM… read more here.
Keywords: bcm; bicyclomycin; gene cluster; distantly related ... See more keywords
Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02220-22
Abstract: Novel retroviruses can emerge from recombination between distantly related retroviruses. Most notably, HIV-1 originated from zoonotic transmission of a novel recombinant (SIVcpz) into humans. ABSTRACT Frequent recombination is a hallmark of retrovirus replication. In rare… read more here.
Keywords: adaptation; hiv; replication; distantly related ... See more keywords
Conserved Patterns in Developmental Processes and Phases, Rather than Genes, Unite the Highly Divergent Bilateria
Sign Up to like & getrecommendations! Published in 2020 at "Life"
DOI: 10.3390/life10090182
Abstract: Bilateria are the predominant clade of animals on Earth. Despite having evolved a wide variety of body plans and developmental modes, they are characterized by common morphological traits. By default, researchers have tried to link… read more here.
Keywords: patterns developmental; processes phases; bilateria; conserved patterns ... See more keywords