Articles with "distinct concerted" as a keyword



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A distinct concerted mechanism of structural dynamism defines activity of human serine protease HtrA3

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Published in 2020 at "Biochemical Journal"

DOI: 10.1042/bcj20190706

Abstract: Human HtrA3 (high-temperature requirement protease A3) is a trimeric multitasking propapoptotic serine protease associated with critical cellular functions and pathogenicity. Implicated in diseases including cancer and pre-eclampsia, its role as a tumor suppressor and potential… read more here.

Keywords: htra3; distinct concerted; activity; serine protease ... See more keywords