Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation
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DOI: 10.7554/elife.76038
Abstract: Key protein adapters couple translation to mRNA decay on specific classes of problematic mRNAs in eukaryotes. Slow decoding on non-optimal codons leads to codon-optimality-mediated decay (COMD) and prolonged arrest at stall sites leads to no-go… read more here.
Keywords: distinct elongation; syh1 smy2; distinct pathways; degradation ... See more keywords