Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
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DOI: 10.1038/s41598-021-03670-5
Abstract: Treatment with a nicotinamide N-methyltransferase inhibitor (NNMTi; 5-amino-1-methylquinolinium) combined with low-fat diet (LD) promoted dramatic whole-body adiposity and weight loss in diet-induced obese (DIO) mice, rapidly normalizing these measures to age-matched lean animals, while LD… read more here.
Keywords: age matched; mice; dio mice; distinct microbiome ... See more keywords