Articles with "distinct phenotypes" as a keyword



Distinct Phenotypes Induced by Three Degrees of Transverse Aortic Constriction in Mice

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-42209-7

Abstract: Transverse aortic constriction (TAC) is a well-established model of pressure overload-induced cardiac hypertrophy and failure in mice. The degree of constriction “tightness” dictates the TAC severity and is determined by the gauge (G) of needle… read more here.

Keywords: distinct phenotypes; aortic constriction; tac; mice ... See more keywords

Long COVID exhibits clinically distinct phenotypes at 3–6 months post-SARS-CoV-2 infection: results from the P4O2 consortium

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Published in 2024 at "BMJ Open Respiratory Research"

DOI: 10.1136/bmjresp-2023-001907

Abstract: Background Four months after SARS-CoV-2 infection, 22%–50% of COVID-19 patients still experience complaints. Long COVID is a heterogeneous disease and finding subtypes could aid in optimising and developing treatment for the individual patient. Methods Data… read more here.

Keywords: sars cov; distinct phenotypes; cluster; cov infection ... See more keywords

Distinct Phenotypes of Myeloid Neoplasia Associated with Truncating C-CBL Mutations

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Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-209834

Abstract: Introduction. Canonical missense (MS) c-CBL mutations affecting linker and zinc finger domains impair protein ubiquitination function and are the most encountered in myeloid neoplasia (MN). However, c-CBL truncations can be also observed with consequential impairment… read more here.

Keywords: cbl mutations; patients mutations; distinct phenotypes; aml ... See more keywords

Chondrocytes from Osteoarthritis Patients Adopt Distinct Phenotypes in Response to Central TH1/TH2/TH17 Cytokines

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22179463

Abstract: Chronic low-grade inflammation plays a central role in the pathogenesis of osteoarthritis (OA), and several pro- and anti-inflammatory cytokines have been implicated to mediate and regulate this process. Out of these cytokines, particularly IFNγ, IL-1β,… read more here.

Keywords: cells macrophages; patients adopt; distinct phenotypes; osteoarthritis patients ... See more keywords