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Distinct pre-initiation steps in human mitochondrial translation

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Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-16503-2

Abstract: Translation initiation in human mitochondria relies upon specialized mitoribosomes and initiation factors, mtIF2 and mtIF3, which have diverged from their bacterial counterparts. Here we report two distinct mitochondrial pre-initiation assembly steps involving those factors. Single-particle… read more here.

Keywords: initiation; mitochondria; translation; initiation factors ... See more keywords