Distinct roles of salt cations and anions upon the salting-out of electro-positive albumin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.112409
Abstract: Abstract Precipitation experiments of electro-positive albumin by the action of a wide number of salts, and at different concentrations, were performed at a constant temperature (25 °C). The pH range studied covered extreme acidic conditions up… read more here.
Keywords: salt cations; electro positive; roles salt; cations anions ... See more keywords
Cerebral μ-opioid and CB1 receptor systems have distinct roles in human feeding behavior
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01559-5
Abstract: Eating behavior varies greatly between individuals, but the neurobiological basis of these trait-like differences in feeding remains poorly understood. Central μ-opioid receptors (MOR) and cannabinoid CB 1 receptors (CB 1 R) regulate energy balance via… read more here.
Keywords: cb1 receptor; cerebral opioid; receptor systems; opioid cb1 ... See more keywords
Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15274-0
Abstract: Despite histone H2A variants and acetylation of histones occurring in almost every eukaryotic organism, it has been difficult to establish direct functional links between canonical histones or H2A variant acetylation, deposition of H2A variants and… read more here.
Keywords: transcription; acetylation; h2a acetylation; deposition ... See more keywords
Distinct roles of immunoreceptor tyrosine‐based motifs in immunosuppressive indoleamine 2,3‐dioxygenase 1
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.12954
Abstract: The enzyme indoleamine 2,3‐dioxygenase 1 (IDO1) catalyses the initial, rate‐limiting step in tryptophan (Trp) degradation, resulting in tryptophan starvation and the production of immunoregulatory kynurenines. IDO1's catalytic function has long been considered as the one… read more here.
Keywords: tyrosine based; tyrosine; immunoreceptor tyrosine; indoleamine dioxygenase ... See more keywords
Distinct roles for canonical and variant histone H3 lysine-36 in Polycomb silencing
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adf2451
Abstract: Polycomb complexes regulate cell-type specific gene expression programs through heritable silencing of target genes. Trimethylation of histone H3 lysine 27 (H3K27me3) is essential for this process. Perturbation of H3K36 is thought to interfere with H3K27me3.… read more here.
Keywords: histone lysine; polycomb silencing; histone; distinct roles ... See more keywords
EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008018
Abstract: Key Points • EVI1 exerts distinct roles in AML, including resistance, pathogenicity of aggressive diseases independent of stemness, and immune evasion.• ERG and cyclin D1 are leukemia-specific targets of EVI1, providing potential therapeutic vulnerability of… read more here.
Keywords: roles aml; erg cyclin; evi1 exerts; exerts distinct ... See more keywords
Distinct roles of GRIN2A and GRIN2B variants in neurological conditions
Sign Up to like & getrecommendations! Published in 2019 at "F1000Research"
DOI: 10.12688/f1000research.18949.1
Abstract: Rapid advances in sequencing technology have led to an explosive increase in the number of genetic variants identified in patients with neurological disease and have also enabled the assembly of a robust database of variants… read more here.
Keywords: roles grin2a; neurological conditions; variants neurological; grin2a grin2b ... See more keywords
Distinct roles of graphene and graphene oxide nanosheets in regulating phospholipid flip-flop.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of colloid and interface science"
DOI: 10.2139/ssrn.3951685
Abstract: Two-dimensional (2D) nanomaterials, such as graphene nanosheets (GNs) and graphene oxide nanosheets (GOs), could adhere onto or insert into a biological membrane, leading to a change in membrane properties and biological activities. Consequently, GN and… read more here.
Keywords: distinct roles; oxide nanosheets; graphene oxide; flip flop ... See more keywords
Distinct Roles of Hemocytes at Different Stages of Infection by Dengue and Zika Viruses in Aedes aegypti Mosquitoes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.660873
Abstract: Aedes aegypti mosquitoes are vectors for arboviruses of medical importance such as dengue (DENV) and Zika (ZIKV) viruses. Different innate immune pathways contribute to the control of arboviruses in the mosquito vector including RNA interference,… read more here.
Keywords: roles hemocytes; aedes aegypti; aegypti mosquitoes; dengue ... See more keywords
ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14235896
Abstract: Simple Summary The dysregulation of ACSL3 and ACSL4, which belong to the long-chain fatty acyl CoA synthetase family (ACSLs), affects the behavior of various cancer cells. This review presents their distinct roles in ferroptosis and… read more here.
Keywords: acsl3 acsl4; cancers acsl3; roles ferroptosis; ferroptosis ... See more keywords
Distinct Roles of Ena ATP Family Proteins in Sodium Accumulation, Invasive Growth, and Full Virulence in Colletotrichum gloeosporioides
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9050566
Abstract: Colletotrichum gloeosporioides, a significant fungal pathogen of crops and trees, causes large economic losses worldwide. However, its pathogenic mechanism remains totally unclear. In this study, four Ena ATPases (Exitus natru-type adenosine triphosphatases), homology of yeast… read more here.
Keywords: full virulence; sodium accumulation; colletotrichum gloeosporioides; distinct roles ... See more keywords