Articles with "distinct transcriptional" as a keyword



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PD‐1‐induced proliferating T cells exhibit a distinct transcriptional signature

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Published in 2021 at "Immunology"

DOI: 10.1111/imm.13388

Abstract: Ligation of the inhibitory receptor PD‐1 on T cells results in the inhibition of numerous cellular functions. Despite the overtly inhibitory outcome of PD‐1 signalling, there are additionally a collection of functions that are activated.… read more here.

Keywords: distinct transcriptional; induced proliferating; exhibit distinct; proliferating cells ... See more keywords
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The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosus

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1072598

Abstract: Introduction Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) present with a complex phenotype and are associated with high mortality and multi-organ involvement. We sought to define the transcriptional landscape and molecular endotypes of AAVs and compare… read more here.

Keywords: molecular endotypes; distinct transcriptional; systemic lupus; analysis ... See more keywords