Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody
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DOI: 10.1016/j.cell.2018.12.006
Abstract: The angiotensin II (AngII) type 1 receptor (AT1R) is a critical regulator of cardiovascular and renal function and is an important model for studies of G-protein-coupled receptor (GPCR) signaling. By stabilizing the receptor with a… read more here.
Keywords: distinctive activation; activation mechanism; nanobody; angiotensin ... See more keywords