Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker
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DOI: 10.1038/s41467-021-24036-5
Abstract: The mechanism behind transgenerational epigenetic inheritance is unclear, particularly through the maternal grandparental line. We previously showed that disruption of folate metabolism in mice by the Mtrr hypomorphic mutation results in transgenerational epigenetic inheritance of… read more here.
Keywords: biomarker; inheritance; folate metabolism; defective folate ... See more keywords