Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03998-x
Abstract: The peptide HsTX1[R14A] is a potent and selective blocker of the voltage-gated potassium channel Kv1.3, which is a highly promising target for the treatment of autoimmune diseases and other conditions. In order to assess the… read more here.
Keywords: r14a; vitro vivo; peptide hstx1; hstx1 r14a ... See more keywords
In Vivo Topical and Systemic Distribution Kinetics of Liposomes with Various Properties for Application to Drug Delivery Systems
Sign Up to like & getrecommendations! Published in 2022 at "Sensors and Materials"
DOI: 10.18494/sam3673
Abstract: Liposomes and lipid nanoparticles have been actively researched and developed as drug delivery carriers owing to their many advantages, such as high biocompatibility and degradability. Their in vivo kinetics depend on the route of administration,… read more here.
Keywords: distribution kinetics; delivery; systemic distribution; drug delivery ... See more keywords