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Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.01.012
Abstract: A series of novel 9, 13-disubstituted berberine derivatives have been synthesized and evaluated for the antibacterial activities against Staphylococcus aureus, including Newman strain and multidrug-resistant strains (NRS-1, NRS-70, NRS-100, NRS-108, and NRS-271). Compound 20 shows…
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Keywords:
berberine derivatives;
disubstituted berberine;
synthesis antistaphylococcal;
antistaphylococcal activity ... See more keywords