Catalytic Conjugate Addition of Electron-Rich Heteroarenes to β,β-Disubstituted Enones.
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DOI: 10.1021/acs.orglett.7b01402
Abstract: Catalytic conjugate additions of heteroarenes to β,β-disubstituted enones are reported. Additions of a range of heteroarene nucleophiles, including furans, indoles, a pyrrole, and a thiophene, to a variety of β,β-disubstituted enones occur to form the… read more here.
Keywords: catalytic conjugate; heteroarenes disubstituted; addition electron; conjugate addition ... See more keywords
Cu(II)-Catalyzed Enantioselective β-Boration of β-Trifluoromethyl, β,β-Disubstituted Enones and Esters: Construction of a CF3- and Boron-Containing Quaternary Stereocenter
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DOI: 10.1021/acscatal.8b02543
Abstract: A highly enantioselective Cu(II)-catalyzed borylative reaction of β-trifluoromethyl β,β-disubstituted enones was developed, which provide a facile access to a variety of chiral alkylboronic esters with a quaternary stereocenter including both a trifluoromethyl group and a… read more here.
Keywords: quaternary stereocenter; boron; trifluoromethyl disubstituted; disubstituted enones ... See more keywords