Regioselective Cross-Coupling of Isatogens with Boronic Acids to Construct 2,2-Disubstituted Indolin-3-one Derivatives.
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DOI: 10.1021/acs.orglett.1c02808
Abstract: Herein we present a transition-metal-free cross-coupling reaction of isatogens with boronic acids through a 1,4-metalate shift of a boron "ate" complex. This coupling reaction provides a feasible method to deliver valuable 2,2-disubstituted indolin-3-one derivatives with… read more here.
Keywords: boronic acids; one derivatives; disubstituted indolin; indolin one ... See more keywords
Direct Oxidative Dearomatization of Indoles with Aromatic Ketones: Rapid Access to 2,2-Disubstituted Indolin-3-ones
Sign Up to like & getrecommendations! Published in 2019 at "Synthesis"
DOI: 10.1055/s-0039-1691528
Abstract: A metal-free oxidative dearomatization of indoles with aromatic ketones mediated by TEMPO oxoammonium salt is described. The dearomatization proceeds smoothly and displays a broad substrate scope with respect to both indoles and aromatic ketones in… read more here.
Keywords: aromatic ketones; oxidative dearomatization; disubstituted indolin; indoles aromatic ... See more keywords