Design and Synthesis of 2,5-Disubstituted-1,3,4-Oxadiazole Hybrids Bearing Pyridine and 1,2,3-Triazole Pharmacophores
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DOI: 10.1002/jhet.2672
Abstract: A novel series of 2,5-disubstituted-1,3,4-oxadiazoles decorated with two biodynamic moieties pyridine and 1,2,3-triazole have been successfully synthesized in good yields under mild reaction conditions. The synthesized compounds are valuable for biological activity exploration since three… read more here.
Keywords: design synthesis; hybrids bearing; pyridine triazole; disubstituted oxadiazole ... See more keywords
Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives
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DOI: 10.4103/1735-5362.212051
Abstract: 1,3,4-oxadiazoles are interesting compounds because of their valuable biological effects such as cytotoxic, antibacterial, antifungal, and anti-tubercular activities. Ethyl mandelate was treated with hydrazine hydrate to yield the corresponding acylhydrazide. Some of the 2,5 disubstituted… read more here.
Keywords: oxadiazole derivatives; evaluation disubstituted; antimicrobial evaluation; procedure ... See more keywords