One-Pot Three-Component Cascade Strategy for the Site-Selective Synthesis of 5-Sulfenylated/Selenylated 2,4-Disubstituted Pyrimidines.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c02252
Abstract: We describe an efficient synthesis of 5-sulfenylated/selenylated 2,4-disubstituted pyrimidines through the three-component cascade reaction of readily available enaminones, amidines, and thio/seleno-benzenesulfonates. This reaction simultaneously constructs two C-N bonds and one C-S/Se bond through a one-pot… read more here.
Keywords: disubstituted pyrimidines; three component; sulfenylated selenylated; synthesis sulfenylated ... See more keywords