Click synthesis of 1,4-disubstituted-1,2,3-triazoles catalyzed by melamine-supported CuO nanoparticles as an efficient recyclable catalyst in water
Sign Up to like & getrecommendations! Published in 2020 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-020-04178-9
Abstract: Melamine-supported CuO nanoparticles (M-CuO nanocatalyst) are prepared as a new and efficient recyclable nanocatalyst for the regioselective synthesis of 1,2,3-triazoles in water. This new nanocatalyst was prepared by co-precipitation method and characterized by FT-IR spectral… read more here.
Keywords: disubstituted triazoles; supported cuo; efficient recyclable; cuo nanoparticles ... See more keywords
CuO-Nanoparticles Catalyzed Synthesis of 1,4-Disubstituted-1,2,3-Triazoles from Bromoalkenes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemical Sciences"
DOI: 10.1007/s12039-018-1452-1
Abstract: A novel and efficient protocol involving commercially available CuO nanoparticles (CNP) as catalyst has been developed for the synthesis of 1,2,3-triazoles. A library of 1,4-disubstituted 1,2,3-triazoles has been constructed with good to excellent yields.Graphical AbstractSynopsisA… read more here.
Keywords: disubstituted triazoles; nanoparticles catalyzed; synthesis disubstituted; cuo nanoparticles ... See more keywords
A novel class of 1,4-disubstituted 1,2,3-triazoles: Regioselective synthesis, antimicrobial activity and molecular docking studies
Sign Up to like & getrecommendations! Published in 2020 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2020.10.026
Abstract: Abstract A Novel class of 1,4-disubstituted 1,2,3-triazoles have been synthesized in good to excellent yields via Cu(I) accelerated azide-alkyne click chemistry reaction strategy. The newly synthesized compounds were assessed for their in vitro antimicrobial activity… read more here.
Keywords: disubstituted triazoles; antimicrobial activity; chemistry; class disubstituted ... See more keywords
Design, synthesis, anticancer and antioxidant activities of amide linked 1,4-disubstituted 1,2,3-triazoles
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129255
Abstract: Abstract To explore anticancer and antioxidant agents with improved potency, we synthesized a series of amide linked 1,4-disubstituted 1,2,3-triazoles through click chemistry approach. The structure of synthesized triazoles were characterized by- FTIR, 1H NMR, 13C… read more here.
Keywords: activity; disubstituted triazoles; linked disubstituted; amide linked ... See more keywords
Palladium-catalyzed selective ortho C–H alkoxylation at 4-aryl of 1, 4-disubstituted 1, 2, 3-triazoles
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.130985
Abstract: Abstract The ortho- C–H bonds at C(4)-aryl of 1, 4-disubstituted 1, 2, 3-triazoles were regioselectively alkoxylated in good to excellent yields with under the directing of the triazole ring. Some products were found to exhibit… read more here.
Keywords: disubstituted triazoles; catalyzed selective; ortho alkoxylation; selective ortho ... See more keywords
DABCO-mediated aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to cycloalkenones. Regioselective synthesis of disubstituted 1,2,3-triazoles
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2016.11.125
Abstract: Abstract Aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to 2-cycloalken-1-ones has been studied in the presence of DABCO as organic base. The reactions were carried out in acetonitrile at room temperature to provide 2,4-disubstituted 2H-1,2,3-triazoles as major adducts… read more here.
Keywords: disubstituted triazoles; aryl triazoles; michael addition; aza michael ... See more keywords
Sequencing [3+2]-cycloaddition and multicomponent reactions: A regioselective microwave-assisted synthesis of 1,4-disubstituted 1,2,3-triazoles using ionic liquid supported Cu(II) precatalysts in methanol
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.152273
Abstract: Abstract Heterocyclic compounds with two to three nitrogen atoms play a pivotal role in the normal life cycle of a cell. Further the design and synthesis of a quality heterocyclic compound library with N-atoms as… read more here.
Keywords: ionic liquid; cycloaddition; disubstituted triazoles; liquid supported ... See more keywords
Nickel-Catalyzed Azide-Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b06338
Abstract: Transition-metal-catalyzed or metal-free azide-alkyne cycloadditions are methods to access 1,4- or 1,5-disubstituted 1,2,3-triazoles. Although the copper-catalyzed cycloaddition to access 1,4-disubstituted products has been applied to biomolecular reaction systems, the azide-alkyne cycloaddition to access the complementary… read more here.
Keywords: disubstituted triazoles; cycloaddition access; azide alkyne; access disubstituted ... See more keywords
Pd-catalyzed selective N(3)-ortho C–H arylation of 1,4-disubstituted 1,2,3-triazoles
Sign Up to like & getrecommendations! Published in 2017 at "Organic chemistry frontiers"
DOI: 10.1039/c6qo00834h
Abstract: Pd(OAc)2-catalyzed direct C–H arylation of an arene triazole template has been explored using the triazole ring as a directing group. The N(3)-ortho C–H bond on C(4) aryl of 1,4-disubstituted 1,2,3-triazoles can be selectively arylated, exclusively… read more here.
Keywords: disubstituted triazoles; catalyzed selective; arylation; selective ortho ... See more keywords
CoFe2O4/Cu(OH)2 magnetic nanocomposite: an efficient and reusable heterogeneous catalyst for one-pot synthesis of β-hydroxy-1,4-disubstituted-1,2,3-triazoles from epoxides
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra06038c
Abstract: Magnetically separable CoFe2O4/Cu(OH)2 nanocomposite was prepared and used as a novel heterogeneous catalyst for synthesis of β-hydroxy-1,4-disubstituted-1,2,3-triazoles from epoxides. read more here.
Keywords: disubstituted triazoles; hydroxy disubstituted; triazoles epoxides; synthesis hydroxy ... See more keywords
Regiospecific Aza-Michael Addition of 4-Aryl-1H-1,2,3-triazoles to Chalcones: Synthesis of 2,4-Disubstituted 1,2,3-Triazoles in Basic Medium
Sign Up to like & getrecommendations! Published in 2018 at "Synlett"
DOI: 10.1055/s-0036-1588567
Abstract: A novel metal-free and base-mediated method to display the donor ability of 1,2,3-triazoles for the synthesis of 2,4-disubstituted 1,2,3-triazoles has been developed. A DABCO-promoted aza-Michael addition of 4-aryl NH-1,2,3-triazoles to α,β-unsaturated ketones (chalcones) is presented.… read more here.
Keywords: disubstituted triazoles; addition; michael addition; synthesis disubstituted ... See more keywords