Synthesis and cytotoxicity of novel 14α-O-(1,4-disubstituted-1,2,3-triazolyl) ester derivatives of andrographolide
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DOI: 10.1080/14786419.2019.1628746
Abstract: Abstract A series of novel 14α-O-(1,4-disubstituted-1,2,3-triazolyl) ester derivatives of andrographolide (5a-n) were synthesized from andrographolide (1). For this endeavour, selective esterification at C-14 hydroxyl group of andrographolide (1) with propiolic acid via protection, deprotection strategy… read more here.
Keywords: disubstituted triazolyl; triazolyl ester; ester derivatives; novel disubstituted ... See more keywords