Improving thermostability of (R)‐selective amine transaminase from Aspergillus terreus through introduction of disulfide bonds
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1572
Abstract: To improve the thermostability of (R)‐selective amine transaminase from Aspergillus terreus (AT‐ATA), we used computer software Disulfide by Design and Modelling of Disulfide Bonds in Proteins to identify mutation sites where the disulfide bonds were… read more here.
Keywords: selective amine; disulfide bonds; thermostability; amine transaminase ... See more keywords
Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201901369
Abstract: Computational design of disulfide bonds was performed for lipase from Geobacillus stearothermophilus T6 (LipT6) for enhanced methanol stability and improved biodiesel production. Thirteen double mutants comprising new cysteine pairs were screened and evaluated for their… read more here.
Keywords: stability; biodiesel synthesis; disulfide bonds;
Dynamically Cross‐Linked Polyolefin Elastomers with Disulfide Bonds Fabricated by Free‐Radical Reactive Processing
Sign Up to like & getrecommendations! Published in 2025 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.202500133
Abstract: Objective: Modifying linear polyolefin elastomer (POE) into covalent adaptable networks (CANs) leads to improved mechanical properties and stability, while retaining good processability. read more here.
Keywords: polyolefin elastomers; dynamically cross; linked polyolefin; disulfide bonds ... See more keywords
Structural characterization of intra- and intermolecular disulfide bonds in voltage-dependent anion channel 3 (VDAC3) protein from Rattus norvegicus by high-resolution mass spectrometry
Sign Up to like & getrecommendations! Published in 2025 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-025-06074-w
Abstract: Voltage-dependent anion channels, the most abundant proteins of the mitochondrial outer membrane, are responsible for the exchange of ions and metabolites between cytosol and mitochondria. They participate in the control of glycolytic metabolism through interaction… read more here.
Keywords: intermolecular disulfide; characterization; voltage dependent; dependent anion ... See more keywords
Impact of disulfide bonds on the folding and refolding capability of a novel thermostable GH45 cellulase
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9256-2
Abstract: A new cellulase (TaCel45) of glycoside hydrolase family 45 was identified in the thermophilic fungus Thielavia arenaria XZ7 and was successfully expressed in Pichia pastoris. The specific activities of TaCel45 towards lichenin, sodium carboxymethylcellulose (CMC-Na),… read more here.
Keywords: gh45 cellulase; disulfide bonds; refolding capability; folding refolding ... See more keywords
Role of Disulfide Bonds on DNA Packaging Forces in Bull Sperm Chromatin.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.08.050
Abstract: Short arginine-rich proteins called protamines mediate the near crystalline DNA packaging in most vertebrate sperm cells. Protamines are synthesized during spermiogenesis and condense the paternal genome into a transcriptionally inactive state in late-stage spermatids. Protamines… read more here.
Keywords: disulfide bonds; dna packaging; bonds dna; role disulfide ... See more keywords
Improved production of single domain antibodies with two disulfide bonds by co-expression of chaperone proteins in the Escherichia coli periplasm.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2017.01.007
Abstract: Single domain antibodies are recombinantly expressed variable domains derived from camelid heavy chain antibodies. Natural single domain antibodies can have noncanonical disulfide bonds between their complementarity-determining regions that help position the binding site. In addition,… read more here.
Keywords: domain antibodies; disulfide bond; disulfide bonds; single domain ... See more keywords
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.120116
Abstract: AIMS Adenoviruses that have CNGRCVSGCAGRC peptide inserted into fiber (AdFNGR) or hexon (AdHNGR) protein, respectively, showed increased transduction of endothelial cells. In this study we investigated if cysteines within the CNGRCVSGCAGRC sequence inserted into Ad5… read more here.
Keywords: disulfide bonds; transduction efficiency; adfngr adhngr; ngr retargeted ... See more keywords
Improvement of multiple-responsive shape memory effects of wool through increasing the content of disulfide bonds
Sign Up to like & getrecommendations! Published in 2020 at "Polymer"
DOI: 10.1016/j.polymer.2019.122130
Abstract: Abstract As an ideal smart wearable natural material, α-keratin type mammalian hairs have proved to exhibit multiple-responsive shape memory effects under water, wet, xenon and redox stimuli, in which the inherent disulfide bonds played the… read more here.
Keywords: disulfide bonds; shape; shape memory; multiple responsive ... See more keywords
Electrocatalytic Reduction of Disulfide Bonds across Chemical Modalities.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c01990
Abstract: The chemical properties of disulfides are leveraged in a wide array of applications, ranging from protein-drug conjugates for cancer treatment to self-healing materials. However, disulfide reduction strategies remain severely underdeveloped despite being the key to… read more here.
Keywords: electrocatalytic reduction; chemical; reduction disulfide; reduction ... See more keywords
Reprogrammable, Reprocessible, and Self-Healable Liquid Crystal Elastomer with Exchangeable Disulfide Bonds.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b09246
Abstract: A liquid crystal elastomer (LCE) can be regarded as an integration of mesogenic molecules into a polymer network. The LCE can generate large mechanical actuation when subjected to various external stimuli. Recently, it has been… read more here.
Keywords: crystal elastomer; liquid crystal; disulfide bonds; lce ... See more keywords