Semi-synthesis of disulfide-linked branched tri-ubiquitin mimics
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DOI: 10.1007/s11426-017-9189-6
Abstract: Ubiquitin (Ub) chain isopeptide bond mimics are useful molecules for biochemical and biophysical studies. Herein, we report the semi-synthesis of the disulfide-linked K11/K48-branched tri-Ub (Ub311/48(S–S)), the first example of an isopeptide mimic for the branched… read more here.
Keywords: semi synthesis; synthesis disulfide; synthesis; disulfide linked ... See more keywords
Characterization of Disulfide-Linked Peptides Using Tandem Mass Spectrometry Coupled with Automated Data Analysis Software
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DOI: 10.1007/s13361-017-1855-0
Abstract: AbstractDisulfide bond formation is critical for maintaining structure stability and function of many peptides and proteins. Mass spectrometry has become an important tool for the elucidation of molecular connectivity. However, the interpretation of the tandem… read more here.
Keywords: mass spectrometry; linked peptides; disulfide; software ... See more keywords