A Novel Tolerogenic Antibody Targeting Disulfide-Modified Autoantigen Effectively Prevents Type 1 Diabetes in NOD Mice
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DOI: 10.3389/fimmu.2022.877022
Abstract: Increasing evidence suggested that the islet amyloid polypeptide (IAPP) is an essential autoantigen in the pathogenesis of type 1 diabetes (T1D) in humans and non-obese diabetic (NOD) mice. A unique disulfide containing IAPP-derived peptide KS20… read more here.
Keywords: nod mice; disulfide modified; type diabetes; autoantigen ... See more keywords