Evidence for a Long-Lived, Cu-Coupled and Oxygen-Inert Disulfide Radical Anion in the Assembly of Metallothionein-3 Cu(I)4-Thiolate Cluster.
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DOI: 10.1021/jacs.1c03984
Abstract: The human copper-binding protein metallothionein-3 (MT-3) can reduce Cu(II) to Cu(I) and form a polynuclear Cu(I)4-Cys5-6 cluster concomitant with intramolecular disulfide bonds formation, but the cluster is unusually inert toward O2 and redox-cycling. We utilized… read more here.
Keywords: spectroscopy; long lived; disulfide radical; cluster ... See more keywords
Disulfide Radical Anion as a Super-Reductant in Biology and Photoredox Chemistry
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DOI: 10.1039/d3sc01867a
Abstract: Disulfides are involved in a broad range of radical-based synthetic organic and biochemical transformations. In particular, the reduction of a disulfide to the corresponding radical anion, followed by S–S bond... read more here.
Keywords: anion super; chemistry; disulfide radical; radical anion ... See more keywords