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Published in 2017 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-017-1157-7
Abstract: Two new diterpene alkaloids having an N-methyladenine moiety, agelamasines A (1) and B (2), were isolated from an Okinawan marine sponge Agelas sp. The structures of 1 and 2 were elucidated on the basis of…
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Keywords:
okinawan marine;
diterpene alkaloids;
sponge agelas;
agelamasines diterpene ... See more keywords
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Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2019.1586916
Abstract: Abstract Diterpene alkaloids (DAs) have a broad spectrum of pharmacological activities, but exhibiting extremely serious cardiotoxicity to induce arrhythmia, heart arrest, even death. This study aimed to evaluate the cardiotoxicity of three diester diterpene alkaloids…
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Keywords:
heart rates;
diterpene alkaloids;
diterpene;
cardiotoxicity ... See more keywords