Agelamasines A and B, diterpene alkaloids from an Okinawan marine sponge Agelas sp.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-017-1157-7
Abstract: Two new diterpene alkaloids having an N-methyladenine moiety, agelamasines A (1) and B (2), were isolated from an Okinawan marine sponge Agelas sp. The structures of 1 and 2 were elucidated on the basis of… read more here.
Keywords: okinawan marine; diterpene alkaloids; sponge agelas; agelamasines diterpene ... See more keywords
Cardiotoxicity evaluation and comparison of diterpene alkaloids on zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2019.1586916
Abstract: Abstract Diterpene alkaloids (DAs) have a broad spectrum of pharmacological activities, but exhibiting extremely serious cardiotoxicity to induce arrhythmia, heart arrest, even death. This study aimed to evaluate the cardiotoxicity of three diester diterpene alkaloids… read more here.
Keywords: heart rates; diterpene alkaloids; diterpene; cardiotoxicity ... See more keywords