Diterpenoid Alkaloids from the Roots of Aconitum iochanicum
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DOI: 10.1007/s10600-020-03069-0
Abstract: Three new diterpenoid alkaloids, namely 1-N-deethyl-1,16-demethoxy-1,16-dihydroxy-N(19)-enaustroconitine A (1), 1-N-deethyl-1,16-demethoxy-1,16-dihydroxy-18-methoxy-N(19)-en-austroconitine A (2), and 1-N-deethyl-1,16-demethoxy-1,16-dihydroxyranaconidine (3), were isolated from the 80% ethanol extract of the roots of Aconitum iochanicum. Structural elucidation of all the compounds was performed… read more here.
Keywords: diterpenoid alkaloids; alkaloids roots; aconitum iochanicum; spectroscopy ... See more keywords
Eleven new C19-diterpenoid alkaloids from Delphinium elatum cv. Pacific Giant.
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DOI: 10.1007/s11418-021-01569-z
Abstract: Diterpenoid alkaloids, the main components of plants of the genera Aconitum, Delphinium, and Garrya, are a group of natural products with notable chemical properties and biological activities. Several C19-diterpenoid alkaloid components from Delphinium elatum cv.… read more here.
Keywords: diterpenoid alkaloids; new c19; c19 diterpenoid; elatum pacific ... See more keywords
Diterpenoid alkaloids with chemotaxonomic significance from Aconitum spathulatum
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DOI: 10.1016/j.bse.2020.104045
Abstract: Abstract Diterpenoid alkaloids have been acknowledged as of chemotaxonomic significance in plants from the genus Aconitum (Ranunculaceae). Phytochemical investigation on the Aconitum spathulatum W. T. Wang, an endemic Aconitum species in China, has led to… read more here.
Keywords: aconitum spathulatum; diterpenoid alkaloids; chemotaxonomic significance; alkaloids chemotaxonomic ... See more keywords
Semi-synthesis and structural elucidation of brevicanines A-D, four new C19-diterpenoid alkaloids with rotameric phenomenon from Aconitum brevicalcaratum.
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DOI: 10.1016/j.fitote.2019.03.012
Abstract: Four new C19-diterpenoid alkaloids brevicanines A-D (1-4) with rotameric phenomenon were isolated from Aconitum brevicalcaratum. They all possessed an unusual axial chiral phenyl-quinazoline side chain and their structures were elucidated by extensive spectroscopic analysis and… read more here.
Keywords: diterpenoid alkaloids; new c19; rotameric phenomenon; four new ... See more keywords
The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.09.022
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE In traditional Chinese medicine, processed aconite root (lateral root of Aconitum carmichaelii Debx.) is used as the principle herb of the Si-Ni decoction (SND) formula due to its cardiotonic effect, while its cardiotoxicity… read more here.
Keywords: diterpenoid alkaloids; root; processed aconite; intestinal bacteria ... See more keywords
Effect of processing on the alkaloids in Aconitum tubers by HPLC-TOF/MS☆
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DOI: 10.1016/j.jpha.2017.01.001
Abstract: According to the Chinese Pharmacopoeia 2015, only processed Aconitum tubers can be clinically applied, and the effect of processing is unclear. This research aimed to explore the effect of processing on cardiac efficacy of alkaloids… read more here.
Keywords: diterpenoid alkaloids; aconitum tubers; effect processing;
Probing the transcriptome of Aconitum carmichaelii reveals the candidate genes associated with the biosynthesis of the toxic aconitine-type C19-diterpenoid alkaloids.
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DOI: 10.1016/j.phytochem.2018.04.022
Abstract: Aconitum carmichaelii has long been used as a traditional Chinese medicine, and its processed lateral roots are known commonly as fuzi. Aconitine-type C19-diterpenoid alkaloids accumulating in the lateral roots are some of the main toxicants… read more here.
Keywords: diterpenoid alkaloids; type c19; aconitine type; c19 diterpenoid ... See more keywords
Four new diterpenoid alkaloids with anti-inflammatory activities from Aconitum taronense Fletcher et Lauener
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DOI: 10.1016/j.phytol.2018.04.001
Abstract: Abstract Four new C19-diterpenoid alkaloids, named taronenines A-D (1-4), have been isolated from the roots of Aconitum taronense Fletcher et Lauener (Ranunculaceae), which has long been used as a folk medicine to treat rheumatism and… read more here.
Keywords: anti inflammatory; diterpenoid alkaloids; aconitum taronense; four new ... See more keywords
C19-diterpenoid alkaloids from Aconitum hemsleyanum var. circinatum
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DOI: 10.1016/j.phytol.2018.07.012
Abstract: Abstract Six new C19-diterpenoid alkaloids, circinatines A–F (1–6), along with eight known compounds, were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated by extensive spectroscopic methods including NMR, IR, HR-ESI-MS… read more here.
Keywords: diterpenoid alkaloids; var circinatum; hemsleyanum var; aconitum hemsleyanum ... See more keywords
Two novel C18-diterpenoid alkaloids, sinomontadine with an unprecedented seven-membered ring A and chloride-containing sinomontanine N from Aconitum sinomontanum
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DOI: 10.1016/j.tetlet.2017.03.013
Abstract: Astract Two new C18-diterpenoid alkaloids, sinomontadine (1) and sinomontanine N (2), were isolated from Aconitum sinomontanum. Their structures were determined by spectroscopic methods and X-ray crystallographic analysis. Sinomontadine (1) features an unprecedented skeleton containing a… read more here.
Keywords: membered ring; diterpenoid alkaloids; c18 diterpenoid; aconitum sinomontanum ... See more keywords
Isolation, Structure Elucidation, Semi-Synthesis, and Structural Modification of C19-Diterpenoid Alkaloids from Aconitum apetalum and Their Neuroprotective Activities.
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DOI: 10.1021/acs.jnatprod.0c01111
Abstract: Five new aconitine-type C19-diterpenoid alkaloids, apetalrines A-E (1-5), were isolated from Aconitum apetalum. Their structures were determined by analysis of 1D and 2D NMR, IR, and HRESIMS data. Semisynthesis of apetalrine B (2) from its… read more here.
Keywords: diterpenoid alkaloids; neuroprotective effects; aconitum apetalum; c19 diterpenoid ... See more keywords