Divergent Evolution of Lanthipeptide Stereochemistry
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00492
Abstract: The three-dimensional structure of natural products is critical for their biological activities and, as such, enzymes have evolved that specifically generate active stereoisomers. Lanthipeptides are post-translationally modified peptidic natural products that contain macrocyclic thioethers featuring… read more here.
Keywords: evolution lanthipeptide; divergent evolution; melan; lanthipeptide stereochemistry ... See more keywords
Divergent evolution of extreme production of variant plant monounsaturated fatty acids
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201160119
Abstract: Significance The dietary and oleochemical value of vegetable oils is determined by their component fatty acids. Double bonds or “unsaturation” in fatty acids are critical for vegetable oil functionality. Seeds containing vegetable oils with extremely… read more here.
Keywords: extreme production; divergent evolution; evolution extreme; fatty acids ... See more keywords
Divergent Evolution of Early Terrestrial Fungi Reveals the Evolution of Mucormycosis Pathogenicity Factors
Sign Up to like & getrecommendations! Published in 2022 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evad046
Abstract: Fungi have evolved over millions of years and their species diversity is predicted to be the second largest on the earth. Fungi have cross-kingdom interactions with many organisms which have mutually shaped their evolutionary trajectories.… read more here.
Keywords: mucormycosis pathogenicity; divergent evolution; biology; evolution ... See more keywords
Two reference-quality sea snake genomes reveal their divergent evolution of adaptive traits and venom systems.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology and evolution"
DOI: 10.1093/molbev/msab212
Abstract: True sea snakes (Hydrophiini) are among the last and most successful clades of vertebrates that show secondary marine adaptation, exhibiting diverse phenotypic traits and lethal venom systems. To better understand their evolution, we generated the… read more here.
Keywords: venom systems; evolution; divergent evolution; sea ... See more keywords
Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac097
Abstract: Abstract Highly diversified astigmatic mites comprise many medically important human household pests such as house dust mites causing ∼1–2% of all allergic diseases globally; however, their evolutionary origin and diverse lifestyles including reversible parasitism have… read more here.
Keywords: astigmatic mites; gene; human household; divergent evolution ... See more keywords
Predicting Parallelism and Quantifying Divergence in Microbial Evolution Experiments
Sign Up to like & getrecommendations! Published in 2022 at "mSphere"
DOI: 10.1128/msphere.00672-21
Abstract: There is currently no framework for identifying genes that contribute to molecular divergence between microbial populations in different environments. To address this absence, we developed a null modeling approach to describe the distribution of mutation… read more here.
Keywords: divergent evolution; divergence microbial; genes contribute; distribution ... See more keywords
Clonal hematopoiesis in angioimmunoblastic T-cell lymphoma with divergent evolution to myeloid neoplasms.
Sign Up to like & getrecommendations! Published in 2020 at "Blood advances"
DOI: 10.1182/bloodadvances.2020001636
Abstract: TET2 and DNMT3A mutations are frequently identified in T-cell lymphomas of T follicular helper cell origin (TCL-TFH), clonal hematopoiesis (CH), and myeloid neoplasms (MNs). The relationships among these 3 entities, however, are not well understood.… read more here.
Keywords: myeloid neoplasms; clonal hematopoiesis; divergent evolution; tcl tfh ... See more keywords
Investigation of NLR Genes Reveals Divergent Evolution on NLRome in Diploid and Polyploid Species in Genus Trifolium
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040867
Abstract: Crop wild relatives contain a greater variety of phenotypic and genotypic diversity compared to their domesticated counterparts. Trifolium crop species have limited genetic diversity to cope with biotic and abiotic stresses due to artificial selection… read more here.
Keywords: divergent evolution; nlr genes; genus trifolium; evolution ... See more keywords