Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.03.018
Abstract: Colonic macrophages are considered to be major effectors of inflammatory bowel diseases (IBDs) and the control of gut inflammation through C-type lectin receptors is an emerging concept. We show that during colitis, the loss of… read more here.
Keywords: divergent roles; inflammation; type lectin; dectin ... See more keywords
Divergent roles for Clusterin in Lung Injury and Repair
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15670-5
Abstract: Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant function of lung epithelial cells. Herein, we report that extracellular Clusterin promoted epithelial cell apoptosis whereas intracellular Clusterin maintained epithelium viability… read more here.
Keywords: epithelial cell; extracellular clusterin; divergent roles; clusterin ... See more keywords
Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis
Sign Up to like & getrecommendations! Published in 2023 at "Virulence"
DOI: 10.1080/21505594.2023.2175914
Abstract: ABSTRACT The sucrose non-fermenting 1 (SNF1) complex is a heterotrimeric protein kinase complex that is an ortholog of the mammalian AMPK complex and is evolutionally conserved in most eukaryotes. This complex contains a catalytic subunit… read more here.
Keywords: candida tropicalis; divergent roles; convergent divergent; snf4 ... See more keywords
Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac079
Abstract: Abstract A major obstacle to successful smoking cessation is the prospect of weight gain. Despite a clear relationship between cigarette smoking and body weight, surprisingly little is known about the physiological and molecular mechanism by… read more here.
Keywords: food; divergent roles; loss; food reward ... See more keywords
Neuronal Network Excitability in Alzheimer’s Disease: The Puzzle of Similar versus Divergent Roles of Amyloid β and Tau
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DOI: 10.1523/eneuro.0418-20.2020
Abstract: Abstract Alzheimer’s disease (AD) is the most frequent neurodegenerative disorder that commonly causes dementia in the elderly. Recent evidence indicates that network abnormalities, including hypersynchrony, altered oscillatory rhythmic activity, interneuron dysfunction, and synaptic depression, may… read more here.
Keywords: alzheimer disease; neuronal network; network excitability; divergent roles ... See more keywords