Divergent transcriptional profiles in pediatric asthma patients of low and high socioeconomic status
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DOI: 10.1002/ppul.23983
Abstract: There are marked socioeconomic disparities in pediatric asthma control, but the molecular origins of these disparities are not well understood. To fill this gap, we performed genome‐wide expression profiling of monocytes and T‐helper cells from… read more here.
Keywords: transcriptional profiles; asthma patients; pediatric asthma; socioeconomic status ... See more keywords
Isotype-specific plasma cells express divergent transcriptional programs
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2121260119
Abstract: Significance During infection, antibodies are produced to target the rapid clearance of initial pathogen with high-affinity variants used long term to protect against reinfection. Under the guidance of CD4 T cell regulation, different subtypes of… read more here.
Keywords: divergent transcriptional; plasma cells; transcriptional programs; specific plasma ... See more keywords
Estrogen regulates divergent transcriptional and epigenetic cell states in breast cancer
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DOI: 10.1093/nar/gkac908
Abstract: Abstract Breast cancers are known to be driven by the transcription factor estrogen receptor and its ligand estrogen. While the receptor's cis-binding elements are known to vary between tumors, heterogeneity of hormone signaling at a… read more here.
Keywords: cell groups; cell; estrogen; divergent transcriptional ... See more keywords