1,3,5‐Triazine: A versatile pharmacophore with diverse biological activities
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000363
Abstract: 1,3,5‐Triazine and its derivatives have been the epicenter of chemotherapeutic molecules due to their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer, antiviral, antimicrobial, anti‐inflammatory, antiamoebic, and antitubercular activities. The present review represents a… read more here.
Keywords: biological activities; triazine versatile; diverse biological; versatile pharmacophore ... See more keywords
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-07524-z
Abstract: The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving 15,212 individuals with epilepsy and 29,677 controls, which reveals 16 genome-wide significant loci, of… read more here.
Keywords: epilepsy; genome wide; mega analysis; diverse biological ... See more keywords
Review on the Diverse Biological Effects of Glabridin
Sign Up to like & getrecommendations! Published in 2023 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s385981
Abstract: Abstract Glabridin is a prenylated isoflavan from the roots of Glycyrrhiza glabra Linne and has posed great impact on the areas of drug development and medicine, due to various biological properties such as anti-inflammation, anti-oxidation,… read more here.
Keywords: effects glabridin; diverse biological; review diverse; medicine ... See more keywords
The Diverse Biological Activity of Recently Synthesized Nitro Compounds
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060717
Abstract: The search for new and efficient pharmaceuticals is a constant struggle for medicinal chemists. New substances are needed in order to treat different pathologies affecting the health of humans and animals, and these new compounds… read more here.
Keywords: nitro compounds; biological activity; diverse biological; activity ... See more keywords
Diverse Biological Activity of Benzofuroxan/Sterically Hindered Phenols Hybrids
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040499
Abstract: Combining two pharmacophores in a molecule can lead to useful synergistic effects. Herein, we show hybrid systems that combine sterically hindered phenols with dinitrobenzofuroxan fragments exhibit a broad range of biological activities. The modular assembly… read more here.
Keywords: diverse biological; benzofuroxan; biological activity; hindered phenols ... See more keywords