Copper-Catalyzed Three-Component Aminofluorination of Alkenes and 1,3-Dienes: Direct Entry to Diverse β-Fluoroalkylamines.
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DOI: 10.1021/jacs.2c09118
Abstract: Rapid and efficient access to structurally diverse β-fluoroalkylamines is in high demand, with their wide presence and great importance in medicinal chemistry and drug development. Direct 1,2-aminofluorination of alkenes offers an ideal strategy for one-step… read more here.
Keywords: diverse fluoroalkylamines; entry; aminofluorination; component aminofluorination ... See more keywords