Chemically Diverse Helix-Constrained Peptides Using Selenocysteine Crosslinking.
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DOI: 10.1021/acs.orglett.8b00233
Abstract: The use of selenocysteines and various cross-linkers to induce helicity in a bioactive peptide is described. The higher reactivity of selenocysteine, relative to cysteine, facilitates rapid cross-linking within unprotected linear peptides under mild aqueous conditions.… read more here.
Keywords: using selenocysteine; chemically diverse; diverse helix; helix constrained ... See more keywords