Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msab131
Abstract: Abstract Emerging evidence links genes within human-specific segmental duplications (HSDs) to traits and diseases unique to our species. Strikingly, despite being nearly identical by sequence (>98.5%), paralogous HSD genes are differentially expressed across human cell… read more here.
Keywords: diverse molecular; mechanisms contribute; expression; human ... See more keywords
Patient-derived organoid elucidates the identical clonal origin of bilateral breast cancer with diverse molecular subtypes
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2024.1361603
Abstract: Bilateral breast cancer (BBC), an infrequent breast cancer subtype, has primarily been studied in terms of incidence, prognosis, and through comparative analysis of synchronous (SBBC) and metachronous (MBBC) manifestations. The advent and application of organoid… read more here.
Keywords: cancer; breast cancer; diverse molecular; bilateral breast ... See more keywords