Microwave-Assisted Synthesis of Diversely Substituted Quinoline-Based Dihydropyridopyrimidine and Dihydropyrazolopyridine Hybrids.
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DOI: 10.1021/acscombsci.7b00091
Abstract: An efficient, catalyst-free, and one-pot three-component procedure for the synthesis of novel and nitrogen rich dihydropyrido[2,3-d]pyrimidines and dihydro-1H-pyrazolo[3,4-b]pyridines bearing a quinoline pharmacophore fragment is provided. Reactions proceeded in DMF under microwave irradiation of three-component mixtures… read more here.
Keywords: microwave assisted; quinoline; assisted synthesis; synthesis ... See more keywords
Selective syntheses of diversely substituted 2-hydroxy-4′-hydroxybenzophenones through [4 + 2] or [3 + 3] annulation of penta-3,4-dien-2-ones with 3-formylchromones
Sign Up to like & getrecommendations! Published in 2017 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00366h
Abstract: A selective synthesis of 2-hydroxy-4′-hydroxybenzophenones or their 3′-acylated counterparts through the cascade reactions of 3-formylchromones with diversely substituted penta-3,4-dien-2-ones is presented. Mechanistically, the formation of the title compounds involves either an unprecedented [4 + 2]… read more here.
Keywords: annulation; hydroxy hydroxybenzophenones; dien ones; selective syntheses ... See more keywords