Improving Diversity in Clinical Trials by Using Real-world Data to Define Eligibility Criteria.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.7170
Abstract: This Viewpoint discusses the need for thoughtful, modernized eligibility criteria with equity prioritization in clinical trials. read more here.
Keywords: improving diversity; eligibility criteria; diversity clinical; clinical trials ... See more keywords
Inclusion and diversity in clinical trials: Actionable steps to drive lasting change.
Sign Up to like & getrecommendations! Published in 2022 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2022.106740
Abstract: BACKGROUND Improving diversity in clinical trials is essential in order to produce generalizable results. Although the importance of representation has become increasingly recognized, identifying strategies to approach this work remains elusive. This article reviews the… read more here.
Keywords: trials actionable; clinical trials; diversity clinical; inclusion diversity ... See more keywords
Diversifying drug development
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DOI: 10.1126/science.371.6529.580-i
Abstract: Genomics Clinical trials frequently underrepresent Black, Latinx, and Indigenous people, and largely involve individuals of European descent. Safety and efficacy testing are thus not performed in a varied group of people that reflects the population… read more here.
Keywords: drug; diversifying drug; drug development; diversity clinical ... See more keywords
Diversity in clinical research: public health and social justice imperatives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Ethics"
DOI: 10.1136/medethics-2021-108068
Abstract: It is well established that demographic representation in clinical research is important for understanding the safety and effectiveness of novel therapeutics and vaccines in diverse patient populations. In recent years, the National Institutes of Health… read more here.
Keywords: representation; health; clinical research; diversity clinical ... See more keywords
Diversity of clinical phenotypes in a cohort of Han Chinese patients with PAX6 variants
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1011060
Abstract: The PAX6 gene plays an important role in ocular development. Mutations of the PAX6 gene may result in a series of ocular abnormalities, including congenital aniridia, anterior segment dysgenesis (ASD), progressive corneal opacification, glaucoma, and… read more here.
Keywords: pax6 gene; diversity clinical; clinical phenotypes; chinese patients ... See more keywords
Gender diversity of clinical practice guideline panels in Australia: important opportunities for progress
Sign Up to like & getrecommendations! Published in 2023 at "Medical Journal of Australia"
DOI: 10.5694/mja2.51832
Abstract: Clinical practice guidelines are recommendations for standards of care that are supported by strong scientific evidence. They can inform individual clinical practice decisions, improve health care quality and safety, and facilitate the translation of research… read more here.
Keywords: practice; diversity clinical; gender diversity; clinical practice ... See more keywords