Substrate recognition diversity and transport dynamics of ABCC1
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DOI: 10.1038/s41467-025-65501-9
Abstract: ABCC1 is an ATP-binding cassette (ABC) transporter that exports diverse endogenous and exogenous substrates, conferring resistance to many anticancer drugs and mediating various physiological functions. Here, we present ten cryo-EM structures of ABCC1 in different… read more here.
Keywords: recognition diversity; transport dynamics; substrate recognition; diversity transport ... See more keywords