Progress toward the Enantioselective Synthesis of Curcusones A-D via a Divinylcyclopropane Rearrangement Strategy.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03829
Abstract: We report our iterative efforts toward the divergent total syntheses of curcusones A-D via Suzuki coupling, intramolecular cyclopropanation, and a key divinylcyclopropane rearrangement. Progress of our synthesis was repeatedly challenged by the highly substrate-dependent cyclopropanation… read more here.
Keywords: curcusones via; progress toward; synthesis; divinylcyclopropane rearrangement ... See more keywords
The total synthesis of (-)-spiroaspertrione A: A divinylcyclopropane rearrangement approach.
Sign Up to like & getrecommendations! Published in 2025 at "Science"
DOI: 10.1126/science.adz7593
Abstract: The rise of multidrug-resistant pathogens poses a major threat to global health, with methicillin-resistant Staphylococcus aureus (MRSA) among the most challenging. One promising approach to overcoming resistance is using small molecules that resensitize MRSA to… read more here.
Keywords: total synthesis; spiroaspertrione; synthesis; approach ... See more keywords