SGLT2 inhibitors and diabetic ketoacidosis: data from the FDA Adverse Event Reporting System
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DOI: 10.1007/s00125-017-4301-8
Abstract: Aims/hypothesisSodium-glucose co-transporter-2 inhibitors (SGLT2i) are indicated for the treatment of type 2 diabetes and may also improve glucose control in type 1 diabetes. In 2015, regulatory agencies warned that SGLT2i may favour diabetic ketoacidosis (DKA).… read more here.
Keywords: dka; reporting; dka reports; reports sglt2i ... See more keywords
Hyperlactatemia in diabetic ketoacidosis is common and can be prolonged: lactate time-series from 25 intensive care admissions
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DOI: 10.1007/s10877-020-00532-9
Abstract: Hyperlactatemia is a documented complication of diabetic ketoacidosis (DKA). Lactate responses during DKA treatment have not been studied and were the focus of this investigation. Blood gas and electrolyte data from 25 DKA admissions to… read more here.
Keywords: dka; mmol; time series; lactate ... See more keywords
Frequency of Diabetic Ketoacidosis in Patients with Type 1 Diabetes Using FreeStyle Libre: A Retrospective Chart Review
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DOI: 10.1007/s12325-021-01765-z
Abstract: Diabetic ketoacidosis (DKA) is an acute complication associated with poorly managed or undiagnosed diabetes. DKA is associated with significant morbidity, mortality, and healthcare costs, but can be prevented with appropriate management of diabetes. The FreeStyle… read more here.
Keywords: dka; chart review; frequency; freestyle libre ... See more keywords
Diabetes-related acute metabolic emergencies in COVID-19 patients: a systematic review and meta-analysis
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DOI: 10.1007/s13340-021-00502-9
Abstract: COVID-19 is associated with diabetic ketoacidosis (DKA), hyperglycaemic hyperosmolar state (HHS) and euglycaemic DKA (EDKA); however, evidence regarding parameters affecting outcome and mortality rates is scarce. A systematic literature review was conducted using EMBASE, PubMed/Medline,… read more here.
Keywords: dka; covid patients; metabolic emergencies; dka hhs ... See more keywords
74 Trends Of Diabetic Ketoacidosis During COVID-19 Pandemic In Large Urban Public Emergency Department
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DOI: 10.1016/j.annemergmed.2021.07.076
Abstract: Study Objectives: Diabetic ketoacidosis (DKA) is a common and serious endocrine emergency. Common triggers for diabetic ketoacidosis include infection, cardiovascular events, drug use, medication non-adherence, and new onset diabetes. Early evidence suggests a correlation between… read more here.
Keywords: dka; covid; covid infection; covid pandemic ... See more keywords
Histological and cognitive alterations in adult diabetic rats following an episode of juvenile diabetic ketoacidosis: Evidence of permanent cerebral injury
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DOI: 10.1016/j.neulet.2017.04.035
Abstract: Evidence suggests that diabetic ketoacidosis (DKA) may cause subtle cognitive alterations in children but the mechanisms are poorly understood. Acute DKA is associated with reactive astrogliosis and microglial activation in a rat model. Whether these… read more here.
Keywords: dka; cognitive alterations; evidence; diabetic ketoacidosis ... See more keywords
Utilizing End-Tidal Carbon Dioxide to Diagnose Diabetic Ketoacidosis in Prehospital Patients with Hyperglycemia
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DOI: 10.1017/s1049023x20000485
Abstract: Abstract Background: Early identification of diabetic ketoacidosis (DKA) may improve clinical outcomes. Prior studies suggest exhaled end tidal carbon dioxide (ETCO2) provides a non-invasive, real-time method to screen for DKA in the emergency department (ED).… read more here.
Keywords: etco2; tidal carbon; dka; end tidal ... See more keywords
Presentation of Severe Diabetic Ketoacidosis in New-Onset Type One Diabetes Mellitus: The Importance of a Broad Differential in an Otherwise Healthy Population in the Operational Environment.
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DOI: 10.1093/milmed/usac266
Abstract: Diabetic ketoacidosis (DKA) is a serious disease entity that must be diagnosed quickly for urgent management in the intensive care unit. Keeping DKA in the differential diagnosis is important, especially in a forward deployed, resource-poor… read more here.
Keywords: otherwise healthy; presentation severe; severe diabetic; diabetic ketoacidosis ... See more keywords
63. Prognosis of COVID-19 Patients with Diabetic Ketoacidosis with or Without Hyperosmolar Hyperglycemic State
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DOI: 10.1093/ofid/ofaa439.373
Abstract: Background: One of the risk factors for poor outcome with SARS-CoV-2 infection is diabetes mellitus;diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are the most serious complications of diabetes mellitus We aimed to explore the… read more here.
Keywords: dka; hyperglycemic state; hyperosmolar hyperglycemic; dka hhs ... See more keywords
421: EFFECT OF POTASSIUM INFUSIONS ON SERUM LEVELS IN CHILDREN DURING TREATMENT OF DIABETIC KETOACIDOSIS
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DOI: 10.1097/01.ccm.0000528439.91797.34
Abstract: www.ccmjournal.org Critical Care Medicine • Volume 46 • Number 1 (Supplement) Learning Objectives: Profound total body potassium deficits occur in children admitted with diabetic ketoacidosis (DKA). However, amount required to maintain normal serum concentration during… read more here.
Keywords: dka; medicine; potassium; treatment ... See more keywords
449: New-Onset Type 1 Diabetes Mellitus in an Adolescent With Ketoacidosis and Severe Hyperosmolar State
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DOI: 10.1097/01.ccm.0000727684.43141.53
Abstract: INTRODUCTION: Diabetic Ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are serious conditions associated with diabetes mellitus (DM) Concurrent DKA and HHS are rare in children, and so far, few cases are reported We report an… read more here.
Keywords: dka; hyperosmolar state; onset type; type ... See more keywords