Associations between the polymorphisms of main components in PI3K/Akt pathway and risk of diabetic kidney disease: A meta-analysis.
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DOI: 10.1002/iub.2711
Abstract: AIMS Diabetic kidney disease (DKD) is a severe microvascular complication frequently associated with type 1 and type 2 diabetes mellitus. The objective of this work was to evaluate the relevance of PI3K/Akt pathway polymorphisms and… read more here.
Keywords: pi3k akt; dkd; meta analysis; akt pathway ... See more keywords
Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease
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DOI: 10.1002/med.21883
Abstract: Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from chronic exposure to hyperglycemia, leading to progressive alterations… read more here.
Keywords: dkd; disease; kidney; metabolomics tool ... See more keywords
Issue focusing: a new topical collection on diabetic nephropathy
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DOI: 10.1007/s00592-018-1228-6
Abstract: Acta Diabetologica has launched a new initiative: a series of Topical Collections starting with this one on Diabetic Nephropathy coordinated by Professor Giuseppe Pugliese and aimed at encouraging the submission of papers on this topic.… read more here.
Keywords: reduction; dkd; disease; prevalence ... See more keywords
Constipation and diabetic kidney disease: The Fukuoka Diabetes Registry
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DOI: 10.1007/s10157-021-02105-9
Abstract: Constipation was shown to be associated with higher risk of end-stage kidney disease or incident chronic kidney disease, although evidence in diabetic patients is lacking. The objective of the present study was to examine the… read more here.
Keywords: constipation; dkd; constipation diabetic; kidney disease ... See more keywords
Mechanism of progression of diabetic kidney disease mediated by podocyte mitochondrial injury.
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DOI: 10.1007/s11033-020-05749-0
Abstract: Diabetic kidney disease (DKD) is an important diabetic microvascular complication, which has become the main cause of end-stage renal disease (ESRD) all over the world. It is of great significance to find effective therapeutic targets… read more here.
Keywords: dkd; disease; diabetic kidney; progression ... See more keywords
Cannabinoid Receptors in Diabetic Kidney Disease
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DOI: 10.1007/s11892-018-0975-7
Abstract: Purpose of ReviewThe purpose of this review is to examine and summarize studies assessing the relevance of the endocannabinoid system (ECS) in diabetic kidney disease (DKD).Recent FindingsEndocannabinoids and endocannabinoid receptors of type 1 (CB1R) and… read more here.
Keywords: kidney; cb1r; dkd; diabetic kidney ... See more keywords
Real-World Diagnosis and Treatment of Diabetic Kidney Disease
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DOI: 10.1007/s12325-021-01777-9
Abstract: People with type 2 diabetes mellitus (T2DM) and diabetic kidney disease (DKD) have increased morbidity and mortality risk. Angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB) are recommended to slow kidney function decline… read more here.
Keywords: kidney; diagnosis; dkd; disease ... See more keywords
SGLT2 Inhibitors: Slowing of Chronic Kidney Disease Progression in Type 2 Diabetes
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DOI: 10.1007/s13300-020-00930-x
Abstract: Diabetic kidney disease (DKD) is a topic of increasing concern among clinicians involved in the management of type 2 diabetes mellitus (T2DM). It is a progressive and costly complication associated with increased risk of adverse… read more here.
Keywords: kidney; dkd; disease; type diabetes ... See more keywords
Mitochondria-targeted drugs for diabetic kidney disease
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DOI: 10.1016/j.heliyon.2022.e08878
Abstract: Diabetic kidney disease (DKD) is one of the most frequent causes of chronic kidney disease (CKD) in the United States. Chronic hyperglycemic conditions are thought to be the primary cause of DKD. However, it is… read more here.
Keywords: dkd; mitochondrial function; diabetic kidney; kidney disease ... See more keywords
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
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DOI: 10.1016/j.ijbiomac.2022.03.077
Abstract: Growing evidence suggests that polysaccharides from traditional Chinese medicine positively affect diabetic kidney disease (DKD) mainly through modulating gut microbiota. Previously, we demonstrated that supplementation with the polysaccharide from Moutan Cortex (MC-Pa) alleviated DKD in… read more here.
Keywords: gut microbiota; dkd; diabetic kidney; kidney disease ... See more keywords
Adropin Carried by Reactive Oxygen Species-Responsive Nanocapsules Ameliorates Renal Lipid Toxicity in Diabetic Mice.
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DOI: 10.1021/acsami.2c06957
Abstract: Diabetic kidney disease (DKD) is a common diabetes complication mainly caused by lipid toxicity characterized by oxidative stress. Studies have shown that adropin (Ad) regulates energy metabolism and may be an effective target to improve… read more here.
Keywords: reactive oxygen; dkd; oxygen species; lipid toxicity ... See more keywords