Granular Cast in Urine Sediment as an Overlooked and Independent Risk Factor for Diabetic Kidney Disease in Type 2 Diabetes Mellitus.
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DOI: 10.1002/dmrr.70113
Abstract: AIM Urine cast analysis is a rapid, cost-effective test that may reflect changes in renal function. In the current study, we evaluated urine cast as a risk factor of the occurrence and severity of diabetic… read more here.
Keywords: risk factor; risk; dkd patients; dkd ... See more keywords
Associations between the polymorphisms of main components in PI3K/Akt pathway and risk of diabetic kidney disease: A meta-analysis.
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DOI: 10.1002/iub.2711
Abstract: AIMS Diabetic kidney disease (DKD) is a severe microvascular complication frequently associated with type 1 and type 2 diabetes mellitus. The objective of this work was to evaluate the relevance of PI3K/Akt pathway polymorphisms and… read more here.
Keywords: pi3k akt; dkd; meta analysis; akt pathway ... See more keywords
Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease
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DOI: 10.1002/med.21883
Abstract: Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from chronic exposure to hyperglycemia, leading to progressive alterations… read more here.
Keywords: dkd; disease; kidney; metabolomics tool ... See more keywords
Issue focusing: a new topical collection on diabetic nephropathy
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DOI: 10.1007/s00592-018-1228-6
Abstract: Acta Diabetologica has launched a new initiative: a series of Topical Collections starting with this one on Diabetic Nephropathy coordinated by Professor Giuseppe Pugliese and aimed at encouraging the submission of papers on this topic.… read more here.
Keywords: reduction; dkd; disease; prevalence ... See more keywords
Attending an integrated nephrology and diabetology outpatient service can improve diabetic kidney disease treatment: a single-center experience
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DOI: 10.1007/s00592-024-02423-w
Abstract: Glucose-lowering medications with established reno-protective effects are still underused in Italy. We explored whether attending an integrated nephrology and diabetology (NPD) outpatient service can improve clinical outcomes and adherence to treatment guidelines for diabetic kidney… read more here.
Keywords: diabetology; dkd; service; outpatient service ... See more keywords
Constipation and diabetic kidney disease: The Fukuoka Diabetes Registry
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DOI: 10.1007/s10157-021-02105-9
Abstract: Constipation was shown to be associated with higher risk of end-stage kidney disease or incident chronic kidney disease, although evidence in diabetic patients is lacking. The objective of the present study was to examine the… read more here.
Keywords: constipation; dkd; constipation diabetic; kidney disease ... See more keywords
Therapeutic targeting of PRSS3 to alleviate kidney damage in DKD
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DOI: 10.1007/s10565-025-10060-4
Abstract: As a primary contributor to end-stage renal disease, diabetic kidney disease (DKD) is characterized by metabolic and inflammatory disturbances. Emerging evidence highlights the gut microbiota's contribution to DKD through metabolite interactions. This study investigates the… read more here.
Keywords: prss3; kidney; gut microbiota; damage ... See more keywords
Canagliflozin Attenuates Podocyte Inflammatory Injury through Suppressing the TXNIP/NLRP3 Signaling Pathway in Diabetic Kidney Disease Mice
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DOI: 10.1007/s10753-025-02258-9
Abstract: Diabetic kidney disease (DKD), a leading cause of end-stage renal disease (ESRD), poses a serious threat to global health. Aseptic inflammation and pyroptosis of podocytes are crucial factors contributing to the pathogenesis and progression of… read more here.
Keywords: mice; disease; txnip nlrp3; diabetic kidney ... See more keywords
Mechanism of progression of diabetic kidney disease mediated by podocyte mitochondrial injury.
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DOI: 10.1007/s11033-020-05749-0
Abstract: Diabetic kidney disease (DKD) is an important diabetic microvascular complication, which has become the main cause of end-stage renal disease (ESRD) all over the world. It is of great significance to find effective therapeutic targets… read more here.
Keywords: dkd; disease; diabetic kidney; progression ... See more keywords
Cannabinoid Receptors in Diabetic Kidney Disease
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DOI: 10.1007/s11892-018-0975-7
Abstract: Purpose of ReviewThe purpose of this review is to examine and summarize studies assessing the relevance of the endocannabinoid system (ECS) in diabetic kidney disease (DKD).Recent FindingsEndocannabinoids and endocannabinoid receptors of type 1 (CB1R) and… read more here.
Keywords: kidney; cb1r; dkd; diabetic kidney ... See more keywords
Real-World Diagnosis and Treatment of Diabetic Kidney Disease
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DOI: 10.1007/s12325-021-01777-9
Abstract: People with type 2 diabetes mellitus (T2DM) and diabetic kidney disease (DKD) have increased morbidity and mortality risk. Angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB) are recommended to slow kidney function decline… read more here.
Keywords: kidney; diagnosis; dkd; disease ... See more keywords