Dickkopf 2–Expressing Adenovirus Increases the Survival of Random-Pattern Flaps and Promotes Vasculogenesis in a Rat Model
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000002109
Abstract: Background Dickkopf 2 (DKK2) has important roles in vertebrate development; it inhibits Wnt signaling-related processes, such as axial patterning, limb development, somitogenesis, and eye formation. However, DKK2 also acts as a Wnt signaling agonist. Dickkopf… read more here.
Keywords: dkk2; expressing adenovirus; group; random pattern ... See more keywords
DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Immunology Research"
DOI: 10.1155/2019/8656282
Abstract: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most devastating cancer types despite the improvement of modern medicine. In our present study, we found that dickkopf-related protein 2 (DKK2) shares a higher expression in PDAC… read more here.
Keywords: dkk2; expression; pancreatic ductal; ductal adenocarcinoma ... See more keywords
MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity
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DOI: 10.1177/00220345211070583
Abstract: Tooth agenesis is a common structural birth defect in humans that results from failure of morphogenesis during early tooth development. The homeobox transcription factor Msx1 and the canonical Wnt signaling pathway are essential for “bud… read more here.
Keywords: morphogenesis; dkk2; tooth development; wnt signaling ... See more keywords
Prognostic value of DKK2 from the Dickkopf family in human breast cancer
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DOI: 10.3892/ijo.2018.4588
Abstract: Breast cancer is one of the most frequently diagnosed types of cancer with a high mortality and malignancy rate in women worldwide. The Dickkopf (DKK) protein family, as a canonical Wnt/β-catenin pathway antagonist, has been… read more here.
Keywords: dkk2; prognostic value; family; breast cancer ... See more keywords
Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer
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DOI: 10.7150/thno.30056
Abstract: Angiogenesis is a fundamental process that involves in tumor progression and metastasis. Vascular endothelial growth factor (VEGF) family and their receptors are identified as the most prominent regulators of angiogenesis. However, the clinical efficacy of… read more here.
Keywords: angiogenesis; dkk2; colorectal cancer; crc ... See more keywords