LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "dkk3" as a keyword



Photo by jontyson from unsplash

Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Neuro-Oncology"

DOI: 10.1007/s11060-018-2894-5

Abstract: BackgroundGlioblastoma multiforme (GBM) is the most malignant of brain tumors. Acquired drug resistance is a major obstacle for successful treatment. Earlier studies reported that expression of the multiple drug resistance gene (MDR1) is regulated by… read more here.

Keywords: akt; augments anti; dkk3; anti tumor ... See more keywords
Photo by maxon from unsplash

Binding of Dickkopf-3 to CXCR7 Enhances Vascular Progenitor Cell Migration and Degradable Graft Regeneration

Sign Up to like & get
recommendations! Published in 2018 at "Circulation Research"

DOI: 10.1161/circresaha.118.312945

Abstract: Rationale: Vascular progenitor cells play key roles in physiological and pathological vascular remodeling—a process that is crucial for the regeneration of acellular biodegradable scaffolds engineered as vital strategies against the limited availability of healthy autologous… read more here.

Keywords: vascular progenitor; dkk3; migration; progenitor ... See more keywords
Photo by ospanali from unsplash

Role of Dickkopf-3 in Blood Pressure Regulation in Mice and Hypertensive Rats

Sign Up to like & get
recommendations! Published in 2023 at "Circulation Research"

DOI: 10.1161/circresaha.122.321744

Abstract: Background: Dkk3 (Dickkopf-3) is a secreted glycoprotein known for its proapoptotic and angiogenic activity. The role of Dkk3 in cardiovascular homeostasis is largely unknown. Remarkably, the Dkk3 gene maps within a chromosome segment linked to… read more here.

Keywords: role; dkk3; expression; stroke ... See more keywords
Photo by neom from unsplash

DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage

Sign Up to like & get
recommendations! Published in 2020 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-020-01794-5

Abstract: Background Intracerebral hemorrhage (ICH) is the most devastating stroke subtype, with a poor prognosis and few proven treatments. Neuroinflammation is associated with ICH-induced brain injury and unfavorable outcomes. There is growing evidence that Dickkopf (DKK)… read more here.

Keywords: kremen dvl; intracerebral hemorrhage; following intracerebral; dkk3 ... See more keywords
Photo by nci from unsplash

The Dkk3 gene encodes a vital intracellular regulator of cell proliferation

Sign Up to like & get
recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0181724

Abstract: Members of the Dickkopf (Dkk) family of Wnt antagonists interrupt Wnt-induced receptor assembly and participate in axial patterning and cell fate determination. One family member, DKK3, does not block Wnt receptor activation. Loss of Dkk3… read more here.

Keywords: cell proliferation; catenin; dkk3; gene ... See more keywords
Photo by art_almighty from unsplash

miR-25-3p protects renal tubular epithelial cells from apoptosis induced by renal IRI by targeting DKK3

Sign Up to like & get
recommendations! Published in 2021 at "Open Life Sciences"

DOI: 10.1515/biol-2021-0127

Abstract: Abstract Renal ischemia-reperfusion injury (IRI) is one of the main causes of acute kidney injury (AKI). So far, there have been many studies on renal IRI, although an effective treatment method has not been developed.… read more here.

Keywords: mir protects; dkk3; mir; apoptosis ... See more keywords
Photo from wikipedia

Apogossypolone Inhibits Cell Proliferation and Epithelial-Mesenchymal Transition in Cervical Cancer via Activating DKK3

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.948023

Abstract: Apogossypolone (ApoG2), a novel derivative of gossypol lacking of two aldehyde groups, exhibits anti-tumor effects. However, the mechanisms by which ApoG2 regulates cervical cancer (CC) cells remain unclear. In this study, we treated two CC… read more here.

Keywords: cervical cancer; cell; cell proliferation; dkk3 ... See more keywords
Photo from wikipedia

Dickkopf-3: Current Knowledge in Kidney Diseases

Sign Up to like & get
recommendations! Published in 2020 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2020.533344

Abstract: Dickkopf-related protein 3 (DKK3) is a secreted glycoprotein that has been implicated in the pathogenesis of a variety of diseases. Recent evidence suggests that urinary DKK3 may serve as a potential biomarker for monitoring kidney… read more here.

Keywords: dickkopf current; kidney; kidney diseases; dkk3 ... See more keywords

Molecular Investigation of DKK3 in Cerebral Ischemic/Reperfusion Injury

Sign Up to like & get
recommendations! Published in 2023 at "Biomedicines"

DOI: 10.3390/biomedicines11030815

Abstract: Dickkopf-3 (Dkk3) is an atypical member of the Dkk family of Wnt inhibitors, which has been implicated in the pathophysiology of neurodegenerative disorders. Its role in the mechanisms of cellular degeneration and protection is still… read more here.

Keywords: wnt catenin; curcumin; dkk3; reperfusion ... See more keywords