Articles with "dko mefs" as a keyword



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Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability

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Published in 2020 at "RNA Biology"

DOI: 10.1080/15476286.2019.1709747

Abstract: ABSTRACT Shortening of mRNA poly(A) tails (deadenylation) to trigger their decay is mediated mainly by the CCR4-NOT deadenylase complex. While four catalytic subunits (CNOT6, 6L 7, and 8) have been identified in the mammalian CCR4-NOT… read more here.

Keywords: ccr4 complex; dko mefs; viability; catalytic subunits ... See more keywords