Association of Disease Location and Treatment With Survival in Diffuse Large B-Cell Lymphoma of the Eye and Ocular Adnexal Region
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.3286
Abstract: Importance Primary diffuse large B-cell lymphoma (DLBCL) of the ocular region is rare, and the utility of surgery and radiation therapy remains unresolved. Objective To explore the clinical characteristics and determine factors associated with overall… read more here.
Keywords: lymphoma; dlbcl; disease; uveal dlbcl ... See more keywords
Apatinib enhances chemosensitivity of ABT‐199 in diffuse large B‐cell lymphoma
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DOI: 10.1002/1878-0261.13309
Abstract: To investigate the effect of Apatinib (an inhibitor targeting VEGFR‐2) enhances chemosensitivity of ABT‐199 on diffuse large B‐cell lymphoma (DLBCL). Viability assay and flow cytometric assay for determining apoptosis, cell cycle, mitochondrial membrane potential, reactive… read more here.
Keywords: cell; abt 199; dlbcl; enhances chemosensitivity ... See more keywords
Safety and activity of ibrutinib in combination with durvalumab in patients with relapsed or refractory follicular lymphoma or diffuse large B‐cell lymphoma
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DOI: 10.1002/ajh.25659
Abstract: This phase 1b/2, multicenter, open‐label study evaluated ibrutinib plus durvalumab in relapsed/refractory follicular lymphoma (FL) or diffuse large B‐cell lymphoma (DLBCL). Patients were treated with once‐daily ibrutinib 560 mg plus durvalumab 10 mg/kg every 2 weeks in… read more here.
Keywords: relapsed refractory; lymphoma; dlbcl; refractory follicular ... See more keywords
USP7 sustains an active epigenetic program via stabilizing MLL2 and WDR5 in diffuse large B-cell lymphoma.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biochemistry and function"
DOI: 10.1002/cbf.3702
Abstract: Activated B-cell-like (ABC)-diffuse large B-cell lymphoma (ABC-DLBCL) is a common subtype of non-Hodgkin's lymphoma with poor prognosis. The survival of ABC-DLBCL relies on constitutive activation of BCR signaling, but the underlying molecular mechanism is not… read more here.
Keywords: dlbcl; lymphoma; cell; abc dlbcl ... See more keywords
REAL‐WORLD BENDAMUSTINE USE IN RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA (R/R DLBCL)
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DOI: 10.1002/hon.100_2631
Abstract: least 12 patients showing a Partial or Complete Response (PR/CR) in stage I. According to the Ray and Rai method less than 15/23 adverse events were also required for the safety coprimary endpoint. Results: From… read more here.
Keywords: real world; dlbcl; safety; world bendamustine ... See more keywords
DIFFUSE LARGE B‐CELL LYMPHOMA: USING IMMUNE BIOMARKERS TO DEFINE NOVEL THERAPIES
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DOI: 10.1002/hon.121_2629
Abstract: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous type of non-Hodgkin’s lymphoma varied from clinical, pathological, immunophenotypic, molecular and prognostic features. According to gene expression profiling, DLBCL can be distinguished to three subtypes, germinal center… read more here.
Keywords: lymphoma; cell; dlbcl; large cell ... See more keywords
Polymorphisms in key regulator genes of the intrinsic apoptosis pathway in risk and clinical presentation of diffuse large B‐cell lymphoma
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DOI: 10.1002/hon.2297
Abstract: To the Editor Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL), accounting for 30–40% of the newly diagnosed cases. Apoptosis is an important mechanism involved in lymphomagenesis, in which… read more here.
Keywords: lymphoma; dlbcl; large cell; diffuse large ... See more keywords
PD1 and PDL1 expression in primary central nervous system diffuse large B‐cell lymphoma are frequent and expression of PD1 predicts poor survival
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DOI: 10.1002/hon.2375
Abstract: Primary central nervous system diffuse large B‐cell lymphoma (PCNS‐DLBCL) is a rare and aggressive type of diffuse large B‐cell lymphoma (DLBCL) whit poorly understood pathogenesis. Finding biomarkers associated with patient survival may be important for… read more here.
Keywords: pd1; dlbcl; large cell; expression ... See more keywords
SIMULTANEOUS DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL) AND FOLLICULAR LYMPHOMA (FL) AT THE DIAGNOSIS HAS SIMILAR OUTCOME AS DLBCL
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DOI: 10.1002/hon.2438_41
Abstract: selected Danish patients as modeled by the CPH model and estimated using the Kaplan‐Meier method. The spread of the CPH curves within each of the IPI groups and overlap between IPI groups illustrates the limitation… read more here.
Keywords: lymphoma; outcome; dlbcl; simultaneous diffuse ... See more keywords
HIGH‐RISK PATIENTS WITH DIFFUSE LARGE B‐CELL LYMPHOMA ARE NOT ENROLLED ON CLINICAL TRIALS
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DOI: 10.1002/hon.2438_42
Abstract: taneous occurrence of DLBCL and FL (DLBCL/FL) in the same lymph node (LN). These pts are treated as DLBCL. The outcome of these pts was not described yet, and these pts are usually excluded from… read more here.
Keywords: outcome; dlbcl; high risk; year ... See more keywords
BMI‐1 protein expression as a negative independent prognostic factor in DLBCL
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DOI: 10.1002/hon.2439_23
Abstract: Meier survival curve analyses with log‐rank test, univariate and multivariate Cox regression model analyses of overall survival (OS), and progression‐free survival (PFS) were performed. Gene ontology (GO) and kyoto encyclopedia of genes and genomes (KEGG)… read more here.
Keywords: dlbcl; melk dlbcl; dlbcl patients; independent prognostic ... See more keywords