Articles with "dlgap1 as2" as a keyword



Long noncoding RNA DLGAP1-AS2 facilitates Wnt1 transcription through physically interacting with Six3 and drives the malignancy of gastric cancer

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Published in 2021 at "Cell Death Discovery"

DOI: 10.1038/s41420-021-00649-z

Abstract: The long noncoding RNA (lncRNA) DLGAP1-AS2 has recently been characterized as an oncogenic lncRNA in several cancers. However, its biological roles and clinical significance in gastric cancer (GC) remains barely understood. In this study, we… read more here.

Keywords: catenin signaling; wnt1; dlgap1; dlgap1 as2 ... See more keywords

Improvement of carboplatin chemosensitivity in lung cancer cells by siRNA-mediated downregulation of DLGAP1-AS2 expression

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-87649-6

Abstract: Despite being one of the primary and most effective treatments for advanced stages of lung cancer, chemotherapy drugs like carboplatin have limitations due to their adverse side effects and the development of drug resistance in… read more here.

Keywords: lung cancer; cancer; cancer cells; dlgap1 as2 ... See more keywords

DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Activates YAP Signaling and Confers Chemoresistance in Squamous Cell Carcinoma.

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Published in 2022 at "Cancer research"

DOI: 10.1158/0008-5472.can-22-0717

Abstract: Squamous cell carcinomas (SCC) constitute a group of human malignancies that originate from the squamous epithelium. Most SCC patients experience treatment failure and relapse and have a poor prognosis due to de novo and acquired… read more here.

Keywords: scc; squamous cell; phosphatidic acid; pld ... See more keywords

Long non-coding RNA DLGAP1-AS1 and DLGAP1-AS2:Two novel oncogenes in multiple cancers.

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Published in 2022 at "Current medicinal chemistry"

DOI: 10.2174/0929867329666220919114919

Abstract: BACKGROUND The change of lncRNA expression is known to affect the progression of tumors. This has fueled numerous investigations aiming at the mystery of lncRNA. Clear lncRNA has been the hotspot of antisense RNAs research.… read more here.

Keywords: as1 dlgap1; dlgap1; dlgap1 as1; dlgap1 as2 ... See more keywords