The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression
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DOI: 10.1002/cac2.12334
Abstract: Elucidation of the post‐transcriptional modification has led to novel strategies to treat intractable tumors, especially glioblastoma (GBM). The ubiquitin‐proteasome system (UPS) mediates a reversible, stringent and stepwise post‐translational modification which is closely associated with malignant… read more here.
Keywords: myc dll1; dll1 notch1; ubiquitin ligase; ligase huwe1 ... See more keywords