Dll4 and Notch signalling couples sprouting angiogenesis and artery formation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Cell Biology"
DOI: 10.1038/ncb3555
Abstract: Endothelial sprouting and proliferation are tightly coordinated processes mediating the formation of new blood vessels during physiological and pathological angiogenesis. Endothelial tip cells lead sprouts and are thought to suppress tip-like behaviour in adjacent stalk… read more here.
Keywords: notch signalling; signalling couples; angiogenesis; formation ... See more keywords
The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ophthalmology"
DOI: 10.1155/2018/3565292
Abstract: Background Retina is the highest oxygen-demanding and vascularized tissue in the body. Retinal development and function require proper vascularization and blood vessel function and integrity. Dll4 is most prominently expressed in the endothelium of angiogenic… read more here.
Keywords: normal pathological; blood vessel; dll4 notch; vessel sprouting ... See more keywords
Preliminary Research of Main Components of Dll4/ Notch-VEGF Signaling Pathway Under High-Glucose Stimulation in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s355004
Abstract: Purpose To establish a high-glucose (HG) stressed cell model and study the expression of main components of the Dll4/Notch-VEGF signaling pathway under high-glucose stimulation. Methods A model of HG-conditioned cells (human umbilical vein endothelial cells,… read more here.
Keywords: notch vegf; main components; dll4 notch; vegf ... See more keywords