A comparison of four methods to estimate dim light melatonin onset: a repeatability and agreement study
Sign Up to like & getrecommendations! Published in 2022 at "Chronobiology International"
DOI: 10.1080/07420528.2022.2150554
Abstract: ABSTRACT Dim light melatonin onset (DLMO) is considered the most reliable circadian phase marker in humans. However, the methods to calculate it are diverse, which limits the comparability between studies. Given the key role of… read more here.
Keywords: agreement; dim light; dlmo; repeatability ... See more keywords
0022 Characterization and Evaluation of Digital Dim Light Melatonin Onset in a Population-Based Sample
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DOI: 10.1093/sleep/zsad077.0022
Abstract: Misalignment between circadian phase (i.e., timing) and the desired sleep window is associated with sleep disturbances including insomnia and circadian rhythm sleep-wake disorders. Identifying circadian-driven sleep disruption requires assessment of circadian phase, the gold-standard of… read more here.
Keywords: digital dlmo; dlmo; based sample; population based ... See more keywords
0620 Dim Light Melatonin Onset Analysis in Individuals Diagnosed with Delayed Sleep-Wake Phase Disorder (DSWPD)
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DOI: 10.1093/sleep/zsad077.0620
Abstract: We are conducting a double-blind, randomized, clinical study in Delayed Sleep-Wake Phase Disorder (DSWPD) participants with extensive clinical phenotyping. We evaluated screening Dim Light Melatonin Onset (DLMO) assessments in participants with a DSWPD diagnosis to… read more here.
Keywords: sleep wake; dlmo; delayed sleep; phase ... See more keywords
0513 The Feasibility of Home-Based Estimation of Circadian Timing in Veterans with Insomnia and past Traumatic Brain Injury: Preliminary Findings
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DOI: 10.1093/sleep/zsaf090.0513
Abstract: Veterans with a history of traumatic brain injury (TBI) are significantly more likely to develop insomnia than their non-injured peers, which contributes to functional impairment and diminished quality of life. Emerging evidence suggests that circadian… read more here.
Keywords: history; tbi; veterans insomnia; circadian timing ... See more keywords
0879 Dim Light Melatonin Onset in a Delayed Sleep-Wake Phase Disorder Cohort: Ongoing Clinical Trial Update
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DOI: 10.1093/sleep/zsaf090.0879
Abstract: We are conducting a double-blind, randomized, clinical study in Delayed Sleep-Wake Phase Disorder (DSWPD) participants with extensive clinical phenotyping. We evaluated screening Dim Light Melatonin Onset (DLMO) assessments in participants with a DSWPD diagnosis to… read more here.
Keywords: sleep wake; delayed sleep; delayed dlmo; phase ... See more keywords
Does cardiovascular autonomic modulation correspond to the increase in dim-light onset of melatonin? A preliminary analysis
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DOI: 10.1152/physiol.2024.39.s1.2442
Abstract: Introduction: The endogenous circadian system promotes the rise in melatonin approximately every 24 hours. In the laboratory, dim light melatonin onset (DLMO) is used as the gold standard method to assess circadian phase. Exogenous melatonin… read more here.
Keywords: cardiovascular autonomic; physiology; autonomic modulation; melatonin ... See more keywords
Identification of a Preliminary Plasma Metabolome-based Biomarker for Circadian Phase in Humans
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biological Rhythms"
DOI: 10.1177/07487304211025402
Abstract: Measuring individual circadian phase is important to diagnose and treat circadian rhythm sleep-wake disorders and circadian misalignment, inform chronotherapy, and advance circadian science. Initial findings using blood transcriptomics to predict the circadian phase marker dim-light… read more here.
Keywords: phase; plasma metabolome; dlmo; circadian phase ... See more keywords