Silencing of long non‐coding RNA DLX6‐AS1 weakens neuroblastoma progression by the miR‐513c‐5p/PLK4 axis
Sign Up to like & getrecommendations! Published in 2020 at "IUBMB Life"
DOI: 10.1002/iub.2392
Abstract: Emerging evidence has demonstrated the crucial roles of long noncoding RNAs in human cancers, including neuroblastoma (NB). DLX6 antisense RNA 1 (DLX6‐AS1) has been identified as an oncogenic driver in NB. However, the mechanisms of… read more here.
Keywords: progression; dlx6 as1; mir 513c; plk4 ... See more keywords
Knockdown of LncRNA DLX6-AS1 inhibits HK-2 cell pyroptosis via regulating miR-223-3p/NLRP3 pathway in lipopolysaccharide-induced acute kidney injury
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-020-09845-5
Abstract: Sepsis-induced acute kidney injury (AKI) represents a severe medical complication. Recently, there is growing evidence indicating the regulatory role of long non-coding RNAs (lncRNAs) in AKI pathophysiology. The present study investigated lncRNA DLX6 antisense RNA… read more here.
Keywords: pyroptosis; dlx6; aki; expression ... See more keywords
Long non-coding RNA DLX6-AS1 regulates neuroblastoma progression by targeting YAP1 via miR-497-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117657
Abstract: AIMS The lncRNA distal-less homeobox 6 antisense 1 (DLX6-AS1) has been reported to be an oncogenic lncRNA in diverse malignant cancers; however, whether it has oncogenic role in neuroblastoma(NB) remain largely unknown. This study explored… read more here.
Keywords: as1 regulates; mir 497; dlx6; expression ... See more keywords
Long non‐coding RNA DLX6‐AS1 is upregulated in preeclampsia and modulates migration and invasion of trophoblasts through the miR‐376c/GADD45A axis
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DOI: 10.1016/j.yexcr.2018.07.039
Abstract: &NA; Long non‐coding RNA (lncRNA) are key regulatory molecules that are implicated in diverse biological processes and human diseases, including preeclampsia. However, their expression and functions in the progression of preeclampsia remains largely unclear. In… read more here.
Keywords: dlx6 as1; as1; migration invasion; mir 376c ... See more keywords
Long non‐coding RNA DLX6‐AS1 mediates proliferation, invasion and apoptosis of endometrial cancer cells by recruiting p300/E2F1 in DLX6 promoter region
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15810
Abstract: Endometrial cancer features abnormal growth of cells of the inner lining of the uterus with the potential to invade to other organs. Accumulating evidence suggests that aberrant expression of long non‐coding RNA (lncRNA) may facilitate… read more here.
Keywords: dlx6; endometrial cancer; cancer cells; cancer ... See more keywords
lncRNA DLX6-AS1 Promotes Myocardial Ischemia-Reperfusion Injury through Mediating the miR-204-5p/FBXW7 Axis
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DOI: 10.1155/2023/9380398
Abstract: Myocardial ischemia-reperfusion (IR) injury is the restoration of blood flow post ischemia, which threatens the human life. Long noncoding RNA distal-less homeobox 6 antisense 1 (DLX6-AS1) has been found to take part in the IR-induced… read more here.
Keywords: dlx6 as1; mir 204; injury; myocardial injury ... See more keywords
A Peptide Encoded by a Long Non-Coding RNA DLX6-AS1 Facilitates Cell Proliferation, Migration, and Invasion by Activating the wnt/β-Catenin Signaling Pathway in Non-Small-Cell Lung Cancer Cell.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2022043172
Abstract: Recently, accumulating study shows that some long non-coding RNAs (lncRNAs) have potential protein/peptide-coding capacities. In this study, the coding potential of lncRNA distal-less homeobox 6 antisense 1 (DLX6-AS1) was examined and the roles and downstream… read more here.
Keywords: cell; wnt catenin; activating wnt; as1 ... See more keywords
LncRNA DLX6-AS1 Promotes the Progression of Neuroblastoma by Activating STAT2 via Targeting miR-506-3p
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DOI: 10.2147/cmar.s252521
Abstract: Background Neuroblastoma (NB) is a common malignant tumor of the sympathetic nervous system, mainly disturbing children. Long non-coding RNAs (lncRNAs) serving as promising cancer biomarkers have been well recognized. Our study intends to explore the… read more here.
Keywords: cell cycle; dlx6 as1; mir 506;
DLX6-AS1: An Indispensable Cancer-related Long Non-coding RNA.
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DOI: 10.2174/1381612826666201029100151
Abstract: BACKGROUND There is increasing evidence that lncRNA, a type of transcript which is over 200 nucleotides in length may serve as oncogenes or suppressor genes are implicated in the pathophysiology of human diseases. In particular,… read more here.
Keywords: cancer; dlx6 as1; rna; lncrna dlx6 ... See more keywords
Association between lncRNAs in plasma exosomes and diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.987488
Abstract: Background Long noncoding RNA (lncRNA) in plasma exosomes is a potential non-invasive diagnostic biomarker for diabetic retinopathy (DR). However, the changes in plasma exosomal lncRNAs and diagnostic relevance in patients with DR patients remain unclear.… read more here.
Keywords: plasma exosomes; diabetic retinopathy; concentration; expression ... See more keywords
Strategies of LncRNA DLX6-AS1 on Study and Therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.871988
Abstract: Accumulating evidence has revealed the vital regulatory roles of lncRNA DLX6-AS1 in various tumors at pre-transcriptional, transcriptional, and post-transcriptional levels, which makes it a potential prognosis factor and therapeutic target. In addition, the presence of… read more here.
Keywords: dlx6 as1; study; research; lncrna dlx6 ... See more keywords