Pharmacological and physiological activation of AMPK improves the spliceopathy in DM1 mouse muscles
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DOI: 10.1093/hmg/ddy245
Abstract: Myotonic dystrophy type 1 (DM1) is a debilitating multisystemic disorder caused by a triplet repeat expansion in the 3' untranslated region of dystrophia myotonica protein kinase mRNAs. Mutant mRNAs accumulate in the nucleus of affected… read more here.
Keywords: dm1 mouse; ampk; activation ampk; dm1 ... See more keywords