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Published in 2017 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2016.4910
Abstract: Duchenne muscular dystrophy (DMD) is a rare, X-linked condition with progressive muscle weakness and accompanying cardiomyopathy. Cardiovascular magnetic resonance (CMR) has proved particularly useful for monitoring the earliest signs of cardiac involvement in DMD, including…
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Keywords:
dmd;
fibrosis;
cardiology;
muscular dystrophy ... See more keywords
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Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.622
Abstract: Duchenne muscular dystrophy (DMD) is the most common form of inherited muscular dystrophy. Germline mutations in dystrophin (DMD) gene cause DMD, with a X‐linked recessive mode of inheritance. Patients with DMD are usually characterized by…
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Keywords:
dmd;
muscular dystrophy;
dystrophy;
application whole ... See more keywords
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Published in 2019 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2019_256
Abstract: Drug development and pharmacotherapy of rare pediatric diseases have significantly expanded over the last decade, in part due to incentives and financial support provided by governments, regulators, and nonprofit foundations. Duchenne muscular dystrophy (DMD) is…
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Keywords:
dmd;
muscular dystrophy;
duchenne muscular;
pharmacotherapy duchenne ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8651-4_16
Abstract: Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder due to the lack of dystrophin production. The disease is characterized by muscle wasting, with the most common causes of death being respiratory failure or heart…
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Keywords:
dmd;
injection peptide;
pcr;
humanized dmd ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8651-4_7
Abstract: Exon skipping through the use of antisense oligonucleotides (AOs) is currently one of the most promising approaches for treating Duchenne muscular dystrophy (DMD). While we now have a number of AO drug candidates in clinical…
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Keywords:
dmd;
muscle cells;
exon;
exon skipping ... See more keywords
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Published in 2017 at "World Journal of Pediatrics"
DOI: 10.1007/s12519-017-0036-3
Abstract: BackgroundNewborn screening for Duchenne muscular dystrophy (DMD) is currently being initiated in Zhejiang Province, China and is under consideration in other countries, including the United States. As China begins to implement DMD newborn screening (DMD-NBS),…
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Keywords:
dmd;
muscular dystrophy;
screening duchenne;
china ... See more keywords
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Published in 2020 at "Drugs"
DOI: 10.1007/s40265-020-01267-2
Abstract: Golodirsen (Vyondys 53 ™ ), an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO) subclass designed to induce exon 53 skipping, has been developed by Sarepta Therapeutics for the treatment of Duchenne muscular dystrophy (DMD).…
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Keywords:
dmd;
first approval;
treatment;
golodirsen ... See more keywords
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Published in 2022 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-022-01784-9
Abstract: Duchenne muscular dystrophy (DMD)-related osteoporosis is of increasing interest due to the extended life expectancy of DMD patients. Although considerable knowledge is available about the pathogenesis of bone fragility in DMD, new clinical and biochemical…
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Keywords:
dmd;
bone;
muscular dystrophy;
fracture ... See more keywords
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Published in 2018 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2017.12.047
Abstract: Abstract The present work is a comparative analysis of Proper Orthogonal Decomposition (POD) and Dynamic Mode Decomposition (DMD) computed on experimental turbulent velocity fields measured in a 20L-tank stirred by two Rushton impellers at two…
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Keywords:
dmd;
analysis;
flow structures;
pod dmd ... See more keywords
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Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.103032
Abstract: Duchenne muscular dystrophy (DMD) is the most common and relentless form of muscular dystrophy. The pleiotropic effects of dystrophin deficiency include remarkable impacts on neuromuscular junction (NMJ) structure and function. Some of these alterations contribute…
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Keywords:
dmd;
muscular dystrophy;
biology;
neuromuscular junction ... See more keywords
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Published in 2020 at "Journal of Wind Engineering and Industrial Aerodynamics"
DOI: 10.1016/j.jweia.2020.104278
Abstract: Abstract This study applies the Dynamic Mode Decomposition (DMD) technique to a prototypical wind engineering problem of flow past a square prism at a Reynolds number of 22,000 to investigate the DMD’s accuracy and practical…
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Keywords:
reconstruction;
dmd;
dynamic mode;
field ... See more keywords